DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uch-L5 and bap1

DIOPT Version :9

Sequence 1:	NP_001261632.1	Gene:	Uch-L5 / 39102	FlyBaseID:	FBgn0011327	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001008206.1	Gene:	bap1 / 493568	XenbaseID:	XB-GENE-494978	Length:	685	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	112/286 - (39%)
Similarity:	160/286 - (55%)	Gaps:	38/286 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPAGKV---- 68
            |..:|||||:||.|:.:||..|.|||||:.|.|   |...|::|.||||||::|.....||
Frog     5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQS---KCPGPVYGFIFLFKWIEERRSRRKVSTLL 66

  Fly    69 ----VLDRE---NIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGL 126
                |::.|   |:|||.|:|.|:|||.|:||:|:|.  ..:.||.||:..|||.:.|.|.:||.
Frog    67 DDTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNC--SGVHLGPTLSRIKEFTKGFSPESKGY 129

  Fly   127 TLSNASQIRTVHNSFARPTLFELDTK----NQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLG 187
            .:.||.::...|||.|||....|..|    :..:..:.:|||.|:||.|||:|||||:..|||.|
Frog   130 AIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLFELDGLKVYPIDHG 194

  Fly   188 EIKSEQNWIDVVRPIIEKRMQRYSDGE----IHFNLMALISDRQRIYEQQIEKLLNPAPNAMDTE 248
            ....::.|.|..|.:|.:|:...:.||    |.|||||::.||:..||.::..|          :
Frog   195 PWAEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRLKYESKLHIL----------K 249

  Fly   249 EDRQAEISSLRTYIEYE----IQKKK 270
            .:||..:.:|:..|...    ||.:|
Frog   250 MNRQTVLEALQQLIRVTQPELIQAQK 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uch-L5	NP_001261632.1	Peptidase_C12_UCH37_BAP1	8..222	CDD:187738	99/232 (43%)
bap1	NP_001008206.1	Peptidase_C12_UCH37_BAP1	5..233	CDD:187738	99/232 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..325		1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	363..425
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	440..493
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	550..579
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	659..685
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q92560	673..678
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1363547at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920