DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uch-L5 and Uchl5

DIOPT Version :9

Sequence 1:	NP_001261632.1	Gene:	Uch-L5 / 39102	FlyBaseID:	FBgn0011327	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001380778.1	Gene:	Uchl5 / 360853	RGDID:	1305414	Length:	329	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	200/333 - (60%)
Similarity:	252/333 - (75%)	Gaps:	15/333 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGDGAGNWCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPA 65
            |...||.|||:|||||||||||:.|||.||||||||||:.|:|:.|:|:|||||||||...:|||
  Rat     1 MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPA 65

  Fly    66 GKVVLDR--ENIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGLTL 128
            |.||.|.  |.|||||||||||||||||:|:|:|..|:|:.|||||:.||||.|.||...|||.|
  Rat    66 GSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLAL 130

  Fly   129 SNASQIRTVHNSFARPTLFELDTKNQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLGEIKSEQ 193
            ||:..||.|||||||..:||.|||...|::|.:|||.|:|:.|||||||||||||||||.. ::.
  Rat   131 SNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGAC-NQD 194

  Fly   194 NWIDVVRPIIEKRMQRYSDGEIHFNLMALISDRQRIYEQQIEKLLN--PAPNAMDTEEDR----- 251
            :||..|||:||||:|:||:|||.|||||::|||:.||||:|.:|..  .....|||::..
  Rat   195 DWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSA 259

  Fly   252 -QAEISSLRTYIEYEIQKKKRYKVENVRRKHNYLPFIVELLKILGENGQLMPIYEKAKQRALERE 315
             |:|::..:..||.|:||.||||:||:||||||||||:||||.|.|:.||:|:.||||    |::
  Rat   260 IQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAK----EKQ 320

  Fly   316 QAQRKKDT 323
            .|::.::|
  Rat   321 NAKKAQET 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uch-L5	NP_001261632.1	Peptidase_C12_UCH37_BAP1	8..222	CDD:187738	145/215 (67%)
Uchl5	NP_001380778.1	Peptidase_C12	8..223	CDD:187736	145/215 (67%)
Uchl5	NP_001380778.1	UCH_C	264..309	CDD:407868	27/44 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353475
Domainoid	1	1.000	64	1.000	Domainoid score	I9913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9326
Inparanoid	1	1.050	345	1.000	Inparanoid score	I2248
OMA	1	1.010	-	-		QHG53985
OrthoDB	1	1.010	-	-		D1363547at2759
OrthoFinder	1	1.000	-	-		FOG0001783
OrthoInspector	1	1.000	-	-		otm44455
orthoMCL	1	0.900	-	-		OOG6_102753
Panther	1	1.100	-	-	LDO	PTHR10589
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1137
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910