DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44838 and ckn

DIOPT Version :9

Sequence 1:	NP_001287006.1	Gene:	CG44838 / 39099	FlyBaseID:	FBgn0266101	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_611009.1	Gene:	ckn / 36673	FlyBaseID:	FBgn0033987	Length:	924	Species:	Drosophila melanogaster

Alignment Length:	701	Identity:	148/701 - (21%)
Similarity:	214/701 - (30%)	Gaps:	217/701 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 QQQQQQQHQQYSHTHLPNGSSATAAADFP------------NYEATTTPQRENSSSVNSGS---- 99
            ||.||..|..:.|   ||..........|            |::|........||.|:|.|
  Fly    34 QQPQQLHHHHHQH---PNHHHPHHQPSIPLYRLSGPLRHHQNHQADDGISMSGSSIVSSPSLEEG 95

  Fly   100 SVNPAHYASAAASASASVEASASAAPTSTPGIAGAAGSTSLTATPSSNRWPTAVATPNGHQSTAS 164
            ..|.....|.|......|..:::||||:  |..|..|:|.:.|.|.....|.....|
  Fly    96 GFNLPRETSVALRLKDEVGGTSTAAPTT--GGPGGGGATVVGAPPPGAGKPGVAMVP-------- 150

  Fly   165 TAGSVPQHFDGSFEFIKYLRHSTDFTPSTPSSATETSSCAEKQVSVSK-SGVQAGATPPPPAQSP 228
                 |...     |...||.     |.|..:|.    ...:|:::.: .|:.  .|..|...||
  Fly   151 -----PPPV-----FCATLRE-----PLTHKAAV----YYHQQLALQEDQGID--LTQSPGRDSP 194

  Fly   229 VAGGLIDLDTSTSQKSRSASRKVAALLSSVSRASNSLVDTSSSALDVFDHDSKQTIFDLQHIASN 293
                     .|:|..:.|.||...|.|.| .|||:.|...|||
  Fly   195 ---------GSSSGSAGSGSRHSTASLDS-GRASSYLTGVSSS---------------------- 227

  Fly   294 GSSNSNESSLEMLAFPNSHLNASNSNTSSEGAACGSAG--------------EFGGLLTGASCSS 344
            |:|         :..|.|....|:.::.|.|:......              |:..|...|....
  Fly   228 GAS---------IRAPLSSPRCSSVSSCSIGSVDRQRNDELIIDWLLEMKHEEYAQLFIAAGYDL 283

  Fly   345 STASSSSHAPKLLGSFVIKENFEVHPSHKVEEGIFQHMNKLPSKKKDTLKQLGVRFTGQMTLTDK 409
            .|.:..:  |:.|.:..||     :|.|:  |.|.|.::||     ..|..|.....|.:....:
  Fly   284 PTIARMT--PEDLTAIGIK-----NPHHR--ERIKQRIDKL-----QVLDNLPHFVPGSIEEWLQ 334

  Fly   410 SIVVENFIKFCEEYDIKDHR-----PWLSLNQCGLNKPEQIKFARYLGQGLPTFTLFCIYSNFKN 469
            .:.:|.:|:...|.:.|..|     .|..|...|:.|         ||.            ..|.
  Fly   335 LLRLEEYIQPLLEQNYKTVRDVTQVTWEDLEDIGIVK---------LGH------------QKKI 378

  Fly   470 LFCTKRTE-------------IYTKDGY-------NLP------YI------LDKTKRF----LA 498
            |...||.:             .|.:..|       |:|      |:      .|.||.:    :.
  Fly   379 LLAIKRVKDIISGKWNPGGANAYQQQEYQRKPWQFNVPIPSTPSYVPTTRVSWDDTKIYATSSVL 443

  Fly   499 NTTA----DLKNMAAANDGSLEFATGSGGGSSSSNN------------SNTCNMNIGSNSNSSVS 547
            |:||    ...|.:.|| |...:.|||.....|.|:            |.....:|..||..|..
  Fly   444 NSTAPSGSSCLNSSLAN-GDAYYCTGSNHECCSGNDVVLIKVRQPRGKSLESLEDIHDNSTRSHL 507

  Fly   548 SGSSNPVLVPGSVINPNAVTMPAGYVTSSTAQQQQHQHQHQHPMTMDPRYGCGAPPALLPPPPLP 612
            :.|.......|....|......|....::|.|||.|..|..|.....      |..|.|.....|
  Fly   508 TFSHYTTTDYGHFGPPTTAAAAAAMAAAATLQQQHHHQQLLHQQQQQ------AAAARLLGNNAP 566

  Fly   613 ALG----------PPPRSLEQLIIYENFDVHETHRIEDGVCTH--ISRLPP 651
            .:|          .|.....:.::||........|.:.|:...  ::.:||
  Fly   567 GIGWRRSYDDGDITPTNDATRELLYEQEGGGTLPRQQRGILQRAVLNTMPP 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44838	NP_001287006.1	PHA03247	<67..230	CDD:223021	39/179 (22%)
CG44838	NP_001287006.1	SOG2	<184..>272	CDD:287409	24/88 (27%)
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896	15/78 (19%)
		SAM	260..316	CDD:197735	15/69 (22%)
		SAM_caskin1,2_repeat2	320..390	CDD:188897	17/90 (19%)
		SAM	326..387	CDD:197735	16/81 (20%)
		Caskin-tail	<887..912	CDD:293238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930