Protein Alignment CG3434 and QTRT1

DIOPT Version :10

• Sequence 1: NP_648320.1
• Gene: CG3434 / 39098
• FlyBaseID: FBgn0036000
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_112486.1
• Gene: QTRT1 / 81890
• HGNCID: 23797
• Length: 403
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 95/432 - (21%)
• Similarity: 168/432 - (38%)
• Gaps: 78/432 - (18%)

  Fly     5 IESISKNSGRLGQLRIRDGGPEFKTPLLL-----QTTKGGSIPWLSA--------DVFETHVSRK 56
            :...|::..|.|:|.:..|  ...||:.:     .|.||.:...|.|        :.:...:...
Human    20 VAECSRSRARAGELWLPHG--TVATPVFMPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPG 82

  Fly    57 PQVLQFTLSTMEQMTEALTHWNSGGGRGLSDYVGLP-------GHLNILLLRDPCETTPSGGNDR 114
            |:::|                   ...||..::..|       |...::.|....|.|..|...|
Human    83 PELIQ-------------------KANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFR 128

  Fly   115 DILPLFTRRGKES-LSSERYMEIVASFKPDMYEGLCDADTNLESAKKRVQKSVDRTEKFM-QYIY 177
            .     ...|.|: ||.|:.::|..:...|:...|.|..::..:. .||::::.|:.::: :.|.
Human   129 S-----PYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTG-PRVEEAMYRSIRWLDRCIA 187

  Fly   178 EHRGKVNSTLLAPIVGGYNTFARTQSIKH--AREQPAGSYGGYIFEGFHANGLSATTLDTSKLLP 240
            .|:......|.|.|.||.:...|...::.  .|:.|          ||...|||... ..|:...
Human   188 AHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVP----------GFAIGGLSGGE-SKSQFWR 241

  Fly   241 IVEHCVKQLEEDKPKILPGAYTPLTVLELIQQGIDVFDTSYAYCASLNFKALSFSFVQDAVEHVP 305
            :|.....:|.:|||:.|.|......::..:..|.|:||..:....:....||           ||
Human   242 MVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSAL-----------VP 295

  Fly   306 F--LDITDEAIKEDFTPPLSNCNCLTCQKHTRAYLHHLYKTNELLGPILLMVHNLYHYMAFFEKI 368
            .  |.:..:..::||.|....|.|.|||||:||:||.|..::.......|.|||:.:.:.....:
Human   296 TGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAV 360

  Fly   369 RESVAKDTLPQLTELVRNQNGKTQVDYSIAANTKVISKATMG 410
            |.|:.:...|   :.||:..|....|.::.......:.|::|
Human   361 RTSIVEKRFP---DFVRDFMGAMYGDPTLCPTWATDALASVG 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3434	NP_648320.1	TGT	13..382	CDD:460299	88/394 (22%)
QTRT1	NP_112486.1	TGT	26..381	CDD:460299	91/406 (22%)
		RNA binding. /evidence=ECO:0000255|HAMAP-Rule:MF_03218	260..266		1/5 (20%)
		RNA binding, important for wobble base 34 recognition. /evidence=ECO:0000255|HAMAP-Rule:MF_03218	284..288		0/3 (0%)