DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3437 and SAC3D1

DIOPT Version :9

Sequence 1:	NP_648318.2	Gene:	CG3437 / 39096	FlyBaseID:	FBgn0035998	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001354414.1	Gene:	SAC3D1 / 29901	HGNCID:	30179	Length:	358	Species:	Homo sapiens

Alignment Length:	362	Identity:	96/362 - (26%)
Similarity:	155/362 - (42%)	Gaps:	44/362 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GSCESFCPDGEAKMRIREKLLHYFELKNG-----QKNKPGVLVKEFTRSAADVKMPMPKEMRTEA 65
            |:|...||..|...|.||..||..|:..|     .:..|...|||::|.||....|.|.::|..:
Human     9 GTCPDMCPAAERAQREREHRLHRLEVVPGCRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPS 73

  Fly    66 ALTKTVEYLLKDIILDTRKPYNVAYDFIFDRLRAVRREIVIQMYDASQKICLLE-------PIVM 123
            .|..||.||..::.............|:.||||||..::.:|....::...:||       .:|.
Human    74 VLLATVRYLAGEVAESADIARAEVASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVA 138

  Fly   124 FLAYSRYRLCEEPIEKFDLKICNQHLQECLTGVLCCYEELEDLESSREPTVRELERRCFIESLYQ 188
            .|.....|...:|:      :....:||....:..||..    .:...|      |:...:.|:.
Human   139 RLGPDAARGPADPV------LLQAQVQEGFGSLRRCYAR----GAGPHP------RQPAFQGLFL 187

  Fly   189 LFNLGSPESFTRALTLPDYVRRDATFKLCFGICLAFQQGN---LYRVLMGVPQLPH--ILCAVAA 248
            |:||||.|:....|.||..:|.....:....:..||::||   |:|:|..:|.||.  :.|.|..
Human   188 LYNLGSVEALHEVLQLPAALRACPPLRKALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGH 252

  Fly   249 AKLQVIRRSLLQIFTHAYNN-KQLTVPVPYLLRLLLFDGPTGLQDQCRHYNISLTADRKAVQFNK 312
            |     ||..|..|..|::. |..|:|:.:::.||..||....:|.|:.:.:.|..:.:.|....
Human   253 A-----RREALARFARAFSTPKGQTLPLGFMVNLLALDGLREARDLCQAHGLPLDGEERVVFLRG 312

  Fly   313 TDFNHNAEVFTPQH--ERFVESKLKRIYIPEVLLLKK 347
               .:..|...|..  :..|||||:...:.||::.::
Human   313 ---RYVEEGLPPASTCKVLVESKLRGRTLEEVVMAEE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3437	NP_648318.2	SAC3_GANP	56..284	CDD:281402	62/240 (26%)
SAC3D1	NP_001354414.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5079
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4977
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49049
OrthoDB	1	1.010	-	-		D1410585at2759
OrthoFinder	1	1.000	-	-		FOG0007450
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107725
Panther	1	1.100	-	-	LDO	PTHR12436
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1280
SonicParanoid	1	1.000	-	-		X4822
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.800