DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3437 and Mcm3ap

DIOPT Version :9

Sequence 1:	NP_648318.2	Gene:	CG3437 / 39096	FlyBaseID:	FBgn0035998	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_006256355.1	Gene:	Mcm3ap / 294339	RGDID:	1306834	Length:	1975	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	88/352 - (25%)
Similarity:	151/352 - (42%)	Gaps:	34/352 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GSCESFCPDGEAKMRIREKLLHYFELKNG-QKNKPGVLVKEFTRSAADVKMPMPKEMRTEAALTK 69
            |:|...||:.|..:|.....|..||:..| .:......|||::||:||.:.|:|.|:|..|.|::
  Rat   633 GTCPDMCPEKERYLRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPSAVLSR 697

  Fly    70 TVEYLLKDIILDTRKPYNVAYDFIFDRLRAVRREIVIQMYDASQKICLLEPIVMFLAYSRYRLCE 134
            |::||:..|:..........|||:::|.|.:|::|..|.......:.|:|....|..:..:.:||
  Rat   698 TMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTRFHIHCAHFMCE 762

  Fly   135 EPIEKFDLKICNQHLQECLTGVLCCYEELEDLESSREPTVRELERRCFIESLYQ----LFNLGSP 195
            ||:..||.||.|:::.:||..:...|::|           |.....|..|:.:|    |.||...
  Rat   763 EPMSSFDAKINNENMTKCLQSLKEMYQDL-----------RNKGVFCASEAEFQGYNVLLNLNKG 816

  Fly   196 ESFTRALTLPDYVRRDATFKLCFGICLAFQQGNLYRVLMGVPQLPHILCAVAAAKLQVIRRSLLQ 260
            :...........||.............|....|..|....|....::...:.......||:..|:
  Rat   817 DILREVQQFHPDVRNSPEVDFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFNQIRKDALR 881

  Fly   261 IFTHAY--NNKQLTV-PVPYLLRLLLFDGPTGLQDQCR------HYNISLTADRKAVQFNKTDFN 316
            ....||  :.::.|| |:..::|:|||       ..|.      :|: .||.....|:.|::.|.
  Rat   882 ALNVAYTVSTQRSTVFPLDGVVRMLLF-------RDCEEATSFLNYH-GLTVADGCVELNRSAFL 938

  Fly   317 HNAEVFTPQHERFVESKLKRIYIPEVL 343
            ....::..:...|:..|| .:.:.||:
  Rat   939 EPEGLYKARKSVFIGRKL-TVSVGEVV 964

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3437	NP_648318.2	SAC3_GANP	56..284	CDD:281402	57/234 (24%)
Mcm3ap	XP_006256355.1	NupH_GANP	2..289	CDD:293373
		Nucleoporin_FG	2..95	CDD:290362
		RRM_MCM3A_like	433..501	CDD:240889
		SAC3_GANP	684..908	CDD:281402	57/234 (24%)
		CID_GANP	1162..1231	CDD:293371
		MCM3AP_GANP	1259..1971	CDD:293374
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5079
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810