DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3437 and F20D12.2

DIOPT Version :9

Sequence 1:	NP_648318.2	Gene:	CG3437 / 39096	FlyBaseID:	FBgn0035998	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_501328.1	Gene:	F20D12.2 / 177589	WormBaseID:	WBGene00017642	Length:	1116	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	75/302 - (24%)
Similarity:	138/302 - (45%)	Gaps:	18/302 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CESFCPDGEAKMRIREKLLHYFE--LKNGQKNKPGVLVKEFTRSAADVKMPMPKEMRTEAALTKT 70
            ||..|.:.|...||.:|.:..:|  :.:|..:.. ::||::.|||||.:.|:|.|:|:|..:.:|
Worm   291 CEEMCTEKERYQRIVQKGVSPYECDIVSGDVSHE-MMVKQYARSAADQERPLPHELRSEKIMNQT 354

  Fly    71 VEYLLKDII---LDTRKPYNVAYDFIFDRLRAVRREIVIQMYDASQKICLLEPIVMFLAYSRYRL 132
            ..|||.:::   .|:.......|:|:::|.||:|:|:.......:..:.|:|..........|.|
Worm   355 TCYLLHNVLDDFPDSADQRGAWYNFLWNRTRALRKEVTQLSLSDTLALNLVERCTRLHILFGYVL 419

  Fly   133 CEEPIEKFDLKICNQHLQECLTGVLCCYEELE--DLESSREPTVRELERRCFIESLYQLFNLGSP 195
            |:..:|:||..:.|:.|.:||..:...||:.|  .:....||..|..:         .:.::...
Worm   420 CDLGVEQFDPAMNNETLGKCLQTLRHLYEDFEKRGISCENEPEFRSYD---------VMLHMNDT 475

  Fly   196 ESFTRALTLPDYVRRDATFKLCFGICLAFQQGNLYRVL-MGVPQLPHILCAVAAAKLQVIRRSLL 259
            ....:.|.....||:....:|...:..||:..|.:|.. :...|..::.|.||.....|.|.:.:
Worm   476 NVLAQVLAYRSEVRQSQPVRLALQLATAFRDNNYFRFFRLLQTQASYLQCCVAHKLFAVTRSNAI 540

  Fly   260 QIFTHAYNNKQLTVPVPYLLRLLLFDGPTGLQDQCRHYNISL 301
            :|.:.:|....:..|:..|.|:|.||....|......|.:.:
Worm   541 RIMSISYGIGNIPYPLDKLQRILGFDNTEDLTVMLNIYELEI 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3437	NP_648318.2	SAC3_GANP	56..284	CDD:281402	55/233 (24%)
F20D12.2	NP_501328.1	SAC3_GANP	291..582	CDD:367477	75/300 (25%)
F20D12.2	NP_501328.1	SPFH_like	<687..788	CDD:388510
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5079
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1280
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840