Protein Alignment phol and Zic3

DIOPT Version :10

• Sequence 1: NP_648317.1
• Gene: phol / 39095
• FlyBaseID: FBgn0035997
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_033601.2
• Gene: Zic3 / 22773
• MGIID: 106676
• Length: 466
• Species: Mus musculus
• Alignment Length: 130
• Identity: 54/130 - (41%)
• Similarity: 69/130 - (53%)
• Gaps: 10/130 - (7%)

  Fly   498 EEPKFRCTHRGCNKEFRNHSAMRKHM---HTHGP--RGHVC--NVC---GKSFVESSKLKRHQLV 552
            ||.:.....:.|::.|.....:..|:   |..||  ..|||  ..|   ||||....||..|..|
Mouse   256 EEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRV 320

  Fly   553 HTGEKPFECTFEGCGKRFSLDFNLRTHVRIHTGDRPYHCPIDGCSKCFAQSTNLKSHMLTHTKPK 617
            |||||||.|.|.||||.|:...||:.|.|.|||::|:.|..:||.:.||.|::.|.||..||..|
Mouse   321 HTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDK 385

  Fly   618  617
            Mouse   386  385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phol	NP_648317.1	COG5048	<504..614	CDD:227381	49/119 (41%)
		C2H2 Zn finger	504..526	CDD:275368	4/24 (17%)
		C2H2 Zn finger	533..553	CDD:275368	9/24 (38%)
		C2H2 Zn finger	561..583	CDD:275368	11/21 (52%)
		C2H2 Zn finger	591..613	CDD:275368	9/21 (43%)
Zic3	NP_033601.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..103
		zf_ZIC	244..289	CDD:436441	6/32 (19%)
		Nuclear localization signal. /evidence=ECO:0000250	296..321		9/24 (38%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
		SFP1	<323..407	CDD:227516	32/63 (51%)
		C2H2 Zn finger	329..351	CDD:275368	11/21 (52%)
		Nuclear localization signal. /evidence=ECO:0000250	329..351		11/21 (52%)
		C2H2 Zn finger	359..381	CDD:275368	9/21 (43%)
		C2H2 Zn finger	389..409	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	403..466