DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3529 and AT1G76970

DIOPT Version :9

Sequence 1:	NP_648315.1	Gene:	CG3529 / 39093	FlyBaseID:	FBgn0035995	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001321321.1	Gene:	AT1G76970 / 844033	AraportID:	AT1G76970	Length:	446	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	121/534 - (22%)
Similarity:	210/534 - (39%)	Gaps:	134/534 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVKN 87
            |.||:..|...:||.|:|:||:||.....|::|::.::|||   ..||::|.:..|..|||..||
plant    10 ERATNDMLIGPDWAINIELCDLINMDPSQAKEAVKVLKKRL---GSKNSKVQILALYALETLSKN 71

  Fly    88 CGKAFHVLVAQKDFINELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQ----PDLNGVTQMYM 148
            ||:..:.|:..:..:|::||::  |..|...::||:|:|:..|.:||..:    |.....   |.
plant    72 CGENVYQLIIDRGLLNDMVKIV--KKKPELNVREKILTLLDTWQEAFGGRGGRYPQYYNA---YN 131

  Fly   149 ELKNKGIEFPANDLDAMAPIYTPQRSVPEMPPQLVAAQQHTISPQHMAAAAAAAAAAAAPPSTGP 213
            :|::.|||||.....::: .:||.::.|:....:.|:
plant   132 DLRSAGIEFPPRTESSLS-FFTPPQTQPDEDAAIQAS---------------------------- 167

  Fly   214 LHLTPEQAAKLR-SELEIVSNNMSILSEMLSVLKPGQESPDDYALLNELTSTCKEMQSRIVDLIG 277
              |..:.|:.|. .|::....::.:|.:||....||........::.:|...|:..|.|::.|:.
plant   168 --LQGDDASSLSLEEIQSAEGSVDVLMDMLGAHDPGNPESLKEEVIVDLVEQCRTYQRRVMTLVN 230

  Fly   278 RVQDDELTAEFLRINDELNNVFLRHQRYEKNRSQGQGAGVTSPSAVLGAAMGLPGVGAAGAGATT 342
            ...|:||..:.|.:||.|.:|..||.                         .:..||:..:....
plant   231 TTTDEELLCQGLALNDNLQHVLQRHD-------------------------DIANVGSVPSNGRN 270

  Fly   343 VATLPPPPTTTAVSNTPQSDQLLIDLIESSEEAQLPQSLGQISLGGGAPIGVQRSARPADEFDML 407
              |..|||..            ::|:....|:.:......:::.....|     :.||.
plant   271 --TRAPPPVQ------------IVDINHDDEDDESDDEFARLAHRSSTP-----TRRPV------ 310

  Fly   408 AQSRTDGNHKSDLLRDIPSVDAAAGSVTATASPYKP---NQPQQAQRSAGEPPVVSKSTKENEID 469
                    |.|    |...||..:|.|      |||   :..|..::....||..|.|:.....|
plant   311 --------HGS----DSGMVDILSGDV------YKPQGNSSSQGVKKPPPPPPHTSSSSSSPVFD 357

  Fly   470 EMEAWLGSSHIEGIEELTSSEFDKFL-------EERAAAAENLPTISASNSAASATTGSAGADSL 527
            :...          ::..|||..:.|       .:|....|:..:.|.|:|:....|.:....|
plant   358 DASP----------QQSKSSEVIRNLPPPPSRHNQRQQFFEHHHSSSGSDSSYEGQTRNLSLTS- 411

  Fly   528 RKTPKKPGAEEDLL 541
             ..|:|....||||
plant   412 -SEPQKEEKPEDLL 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1	17..158	CDD:239623	47/138 (34%)
CG3529	NP_648315.1	GAT_TOM1_like	222..307	CDD:260091	22/85 (26%)
AT1G76970	NP_001321321.1	VHS	10..135	CDD:239620	44/132 (33%)
AT1G76970	NP_001321321.1	GAT_GGA_like_plant	180..258	CDD:260089	21/102 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2574
eggNOG	1	0.900	-	-		E1_KOG1087
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1726
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000599
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X466
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.820