DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3529 and Gga

DIOPT Version :9

Sequence 1:	NP_648315.1	Gene:	CG3529 / 39093	FlyBaseID:	FBgn0035995	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_572571.1	Gene:	Gga / 31902	FlyBaseID:	FBgn0030141	Length:	660	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	112/554 - (20%)
Similarity:	219/554 - (39%)	Gaps:	107/554 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QRIEAATDANLASENWAANMEICDMINESSDTARDAMRAI-RKRLSQNAGKNNQVVMYTLTVLET 83
            :.:|.||:.....:.....| .|.::..::.....|...| .|..|.|..:..:.:    ::||.
  Fly    10 EMLERATNPAQKIDELGVQM-FCIVVKSNAQLVHKAQEMIVAKVRSTNVTEATRAI----SLLEE 69

  Fly    84 CVKNCGKAFHVLVAQKDFINELVKLIGPK---NDPPAAMQEKVLSLIQIWADAFKNQPDLNGVTQ 145
            |:..||..|....::..|:|||::|:..|   .:.|..::::::..:.:|...|   |....:..
  Fly    70 CMTQCGDDFQDEASKFRFLNELIRLVSKKYKGAETPHEVKQRIMECLLLWTTEF---PQRQKIRD 131

  Fly   146 MYMELKNKG-IEFPANDLDAMAPIYTPQRSVPE-MPPQLVAAQQHTISPQHMAAAAAAAAAAAAP 208
            .|..|:.:| ||....:. |:|...:...::.| |..:|:.:.    :|::...|........|.
  Fly   132 AYDMLRKEGDIEHGTTEA-AVAKRESVLGTIDEAMFAKLIKSN----NPENFKRANLLLQYRMAQ 191

  Fly   209 PSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLKPGQESPDDYALLNELTSTCKEMQSRIV 273
            .:.     ..:..|:.|..|..|...|.:|::||....|..:  |....|:||..:||: ...|.
  Fly   192 EAR-----RNDLLAQHRLVLCEVQETMQLLNQMLDTYDPANQ--DVSETLHELYKSCKK-HKPIF 248

  Fly   274 DLIGRVQDD---ELTAEFLRINDELNNVFLRHQRYEKNRSQGQGAGVTSPSAVLGAAMGLPGVGA 335
            ..:.::.||   :|.|:.|..|..|.....|::....:.::...|.:|:.:..:.:::      .
  Fly   249 QHLPQLLDDSDAQLVADTLDANCALLATMQRYKLLVPSPTRSTAAALTTSAPTVASSV------K 307

  Fly   336 AGAGATTVATLPPPPTTTAVSNTPQSDQLLID-LIESSEEA--QLPQSLGQISLGGGAPIG---- 393
            :.|.:||        .||:.:|....::||.| ||:.|.:|  ....||...:..|..|:.
  Fly   308 STASSTT--------ATTSSNNAQLLNELLGDLLIDGSNKAATTATTSLPNAAASGSNPLADLSD 364

  Fly   394 ----------VQRSARPAD------EFDMLAQSRT-----DGNHKS-----DLLRDIPSVDAAAG 432
                      .::.::|..      |..:::|..|     :||..|     :.:|.:|.:|..:.
  Fly   365 IFSSALAESEAKQQSQPFQNATTLLEPQVISQGTTTEALANGNGGSASKVPETIRKMPQIDMLSE 429

  Fly   433 SVTATASPYKPNQPQQAQRSAGEPPVVSKSTKENEIDEMEAWLGSSHIEGIEELTSSEFDKFLEE 497
            .:.....|.:...|...:    :|..::.:....|         ..||:..||.|::
  Fly   430 ELFQQILPTQDRMPSFKR----DPEKITLNDLARE---------RMHIKAPEEPTTA-------- 473

  Fly   498 RAAAAENLPTISASNSAASATTGSAGADSLRKTP 531
                  |.|   ||:||.:..|.:|..||:...|
  Fly   474 ------NDP---ASDSAPAIATATATVDSIDDVP 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1	17..158	CDD:239623	31/142 (22%)
CG3529	NP_648315.1	GAT_TOM1_like	222..307	CDD:260091	24/87 (28%)
Gga	NP_572571.1	VHS_GGA	7..144	CDD:239624	30/141 (21%)
		GAT	210..284	CDD:281166	20/76 (26%)
		Alpha_adaptinC2	543..644	CDD:197886
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2130
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.870