DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3529 and SPAC1F3.05

DIOPT Version :9

Sequence 1:	NP_648315.1	Gene:	CG3529 / 39093	FlyBaseID:	FBgn0035995	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_593008.1	Gene:	SPAC1F3.05 / 2541469	PomBaseID:	SPAC1F3.05	Length:	510	Species:	Schizosaccharomyces pombe

Alignment Length:	462	Identity:	118/462 - (25%)
Similarity:	191/462 - (41%)	Gaps:	69/462 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 STPVGQRIEAATDANLASENWAANMEICDMINE-SSDTARDAMRAIRKRLSQNAGKNNQVVMY-T 77
            |..:.:.|:.|||......|.|.|:||.|:||| ..:|.|:|...|.||::    ..|..|.| .
pombe     4 SQTLSKYIDKATDQFNLEPNLALNIEIADLINEKKGNTPREAALLILKRVN----SANPTVSYLA 64

  Fly    78 LTVLETCVKNCGKAFHVLVAQKDFINELVKLIGPKNDPPAAM---QEKVLSLIQIW----ADAFK 135
            |.:|:.||||||..||..:|.::|:|..|...  .|.|.:.|   |.|:|.:::.|    ....:
pombe    65 LHLLDICVKNCGYPFHFQIASEEFLNGFVSRF--PNHPISRMNKIQSKMLEMLEEWNYMLCKNNR 127

  Fly   136 NQPDLNGVTQMYMELKNKGIEFPANDLDAMAPIYTPQ---RSVPEMPPQLVAAQQHTI------- 190
            ::.|.:.:..:...:..:|.:|||.|.|::| :..|.   ||..|:..:.:.|.:..:
pombe   128 HREDFSRIHDIRELMAFRGYKFPAVDEDSIA-VMKPNNSLRSAQELAREDLEAHKAKLQELLRRG 191

  Fly   191 SPQHMAAAAAAAAAAAAPPSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLK--PGQESPD 253
            :|..:|.|.|.....|......    |.:.:|...::||      ||.|:.|.|.:  ..|....
pombe   192 TPMDLAEANALMKVIAGYDEEN----TEDYSALAAADLE------SIRSKALRVKQFLVNQTVSL 246

  Fly   254 DYALLNELTSTCKEMQSRIVDLIGRVQDDE-LTAEFLRINDELNNVFLRHQRYEKNRSQGQGAGV 317
            :...|.:...:.|..|::|..::....:|| ...:.|.:||.|.||.......:...|   |..|
pombe   247 EEGTLADAVESLKVYQTKIARILREENEDEYYVQKLLSLNDLLINVIEECSNSDLIHS---GTNV 308

  Fly   318 TSPSAVLGAAMGLPGVGAAGAGATTVATLPPPPTTTAVSNTPQSDQLLIDLIESSEEAQLPQSLG 382
            .|..         |.|         |.:..||.     ||..:.:..||||::.:||..:|..
pombe   309 VSSQ---------PNV---------VESHVPPS-----SNDTKQESSLIDLMKLTEEPAVPSP-- 348

  Fly   383 QISLGGGAPIGVQRSARPADEFDMLAQSRTDGNHKSDLLRDIPSVDAAAGSVTATASPYKPNQPQ 447
              ||....|.....|...:....|.:.|....|..|.....||:.:::..|:..:.|.....|..
pombe   349 --SLPTNVPANQSLSMLSSLSNSMSSTSNGALNSPSYSQAAIPNTNSSLTSILQSDSLMISTQLT 411

  Fly   448 QAQRSAG 454
            ..|:|:|
pombe   412 SVQKSSG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1	17..158	CDD:239623	45/149 (30%)
CG3529	NP_648315.1	GAT_TOM1_like	222..307	CDD:260091	21/87 (24%)
SPAC1F3.05	NP_593008.1	VHS	6..146	CDD:250135	44/145 (30%)
		GAT_GGA_fungi	216..304	CDD:260093	21/93 (23%)
		Alpha_adaptinC2	398..507	CDD:197886	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1087
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I1814
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000599
OrthoInspector	1	1.000	-	-		otm47188
orthoMCL	1	0.900	-	-		OOG6_102984
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2130
SonicParanoid	1	1.000	-	-		X466
TreeFam	0	0.000	Not matched by this tool.
	8	7.790