Protein Alignment CG3529 and GGA3

DIOPT Version :9

• Sequence 1: NP_648315.1
• Gene: CG3529 / 39093
• FlyBaseID: FBgn0035995
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_016879874.1
• Gene: GGA3 / 23163
• HGNCID: 17079
• Length: 733
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 132/608 - (21%)
• Similarity: 229/608 - (37%)
• Gaps: 128/608 - (21%)

  Fly    19 GQRIEA----ATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVVMYTLT 79
            |:.:|:    ||:.:...|:|...:..||.||:..:..:.|:|.:..::.   .......:..||
Human     6 GESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQ---SPQEWEALQALT 67

  Fly    80 VLETCVKNCGKAFHVLVAQKDFINELVKLIGPK---NDPPAAMQEKVLSLIQIWADAFKNQPDLN 141
            |||.|:||||:.||..|.:..|:|||:|::.||   :.....::.||:.|:..|..|.   |:..
Human    68 VLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMAL---PEEA 129

  Fly   142 GVTQMYMELKNKGIEFPANDLDAMAPIYTPQRSVPEMPP-------------QLVAAQQHTISPQ 193
            .:...|..||.:||      :.:..||...:..:|..||             :|:|....:.:|.
Human   130 KIKDAYHMLKRQGI------VQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNPD 188

  Fly   194 HMAAAAAAAAAAAAPPSTGPLHLTPEQAAKLRS------ELEIVSNNMSILSEMLSVLKPGQESP 252
            .:..|.....:           :..|..|:::.      .||.|:||:.:|||||........|.
Human   189 DLQEANKLIKS-----------MVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSD 242

  Fly   253 DDYALLNELTSTCKEMQSRIVDLIGRVQD-DELTAEFLRINDELNNVFLRHQR-YEKNRSQGQGA 315
            .|..|:.||...|:..:..:..|....:| |....:.|:.:|.|:.|...::. .|.....|:.|
Human   243 GDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEVA 307

  Fly   316 GVTSP--------------------------SAVLGAAMGLPGVGAAGAGATTVATLPPPPTTTA 354
            .:|.|                          |:||..|...|..|        :..|||||..:.
Human   308 TLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSG--------IPILPPPPQASG 364

  Fly   355 VSNTPQSDQLLIDLIESSEE---AQLPQSLGQISLGGGAPIGVQRSARPADEFDMLAQSRTDGNH 416
            ...:..|.|....|..||..   :.|.:.|..:.|...||....:.:....::.:|.:.::|.:.
Human   365 PPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQSDLDF 429

  Fly   417 KSDL-------LRDIPSVDAAAGSVTATASPYKPNQPQ-------------QAQRSAGEPPVVSK 461
            .|..       ..|.|.:..:|.|.:::.:|..|..|.             .:..|.|..|.::.
Human   430 FSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAGSSLFSTGVAPALAP 494

  Fly   462 STKENEIDEMEAWLGSSHIEGIEELTSSEFDKFLEE--------RAAAAENLPTISASNSAASAT 518
            ..:..........||:|.:..::.|     |:.|||        :...:..:||.:.:......:
Human   495 KVEPAVPGHHGLALGNSALHHLDAL-----DQLLEEAKVTSGLVKPTTSPLIPTTTPARPLLPFS 554

  Fly   519 TGSAGA-------DSLRKTPKKP 534
            ||....       .|....||.|
Human   555 TGPGSPLFQPLSFQSQGSPPKGP 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1	17..158	CDD:239623	43/145 (30%)
		GAT_TOM1_like	222..307	CDD:260091	24/92 (26%)
GGA3	XP_016879874.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1087
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2130
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840