DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nf-YA and nfya-1

DIOPT Version :9

Sequence 1:	NP_648313.1	Gene:	Nf-YA / 39091	FlyBaseID:	FBgn0035993	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_509999.1	Gene:	nfya-1 / 181368	WormBaseID:	WBGene00011614	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	89/382 - (23%)
Similarity:	140/382 - (36%)	Gaps:	129/382 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 TNAAATAQ--PIQVIPMPMLPTGAAQIIIGQQPQGQATATGLQPQLIPLQANQIMLQA------A 121
            |:.|:.:|  |.|..|....|   |.:...:.||...::     .:.|.|..:|. ||      :
Worm    90 THQASVSQTTPTQTTPSQYTP---ASVSTARAPQFHRSS-----HVTPSQQQRIE-QAFGPAPVS 145

  Fly   122 QQQPQMQVMQLPDGQTIFYQTPTIA----------------------ALDPNAAANAAAAMAAQP 164
            |.|||       :|..|.|..|:.:                      :..||...|      .|.
Worm   146 QSQPQ-------NGSYIQYNEPSTSVASTTTSFYSPNESEPVFTHAISFKPNEPEN------GQK 197

  Fly   165 TPHYLNI--NGQLVQINPA--PSANQAAPTA-----GQQIIMVPQTAMAAVNAAAANAGVGAGVG 220
            ....|.:  :|::.:||.:  |:..:..|..     ...:..:|:|.:..:...|....|.|.:.
Worm   198 AREQLELLDSGKINEINQSKVPTTIELPPNCKLFQYSWVLDGIPRTLLVPMPMDATEEDVKAMLP 262

  Fly   221 TVVTQQQQQQHQQVQSQTQNQQQQQQQQTVAAVAASAAVNNISADVSTSTTGTNTNSEDESSKGE 285
            ..:         ::.|...|..:.:.:..|.:.                ..||..|.|   ..|.
Worm   263 KTL---------EMDSNLFNNARPRDELPVLSF----------------PNGTVPNVE---MIGP 299

  Fly   286 ADEEPLYVNAKQYKRILIRRQARAKLES--RIPKERCKYLHESRHRHAMNRARGEGGRFHSAQE- 347
            ..::|:.||.||:.||:.||:.|.:||:  |:|..|.||||||||.||:.|.||..|||.:.:.
Worm   300 KVQQPMLVNPKQFNRIMRRREMRQQLEASGRLPLARQKYLHESRHLHALKRKRGLDGRFDNTKTA 364

  Fly   348 ---------------------KGDQ--DSSG----------PEGG----SMPMASSG 367
                                 .|::  |||.          |:||    |||..|:|
Worm   365 ESSSMVSSTTSPRKLKRRNRLPGEETSDSSSIVLPSPVEIQPKGGIVNSSMPSTSTG 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nf-YA	NP_648313.1	CBF	286..345	CDD:128795	31/60 (52%)
nfya-1	NP_509999.1	PHA03247	<4..84	CDD:223021
nfya-1	NP_509999.1	CBF	300..361	CDD:128795	31/60 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167234
Domainoid	1	1.000	63	1.000	Domainoid score	I6779
eggNOG	1	0.900	-	-		E1_COG5224
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001472
OrthoInspector	1	1.000	-	-		otm14476
orthoMCL	1	0.900	-	-		OOG6_102402
Panther	1	1.100	-	-	LDO	PTHR12632
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R547
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860