DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bet3 and Trappc3

DIOPT Version :9

Sequence 1:	NP_648312.3	Gene:	Bet3 / 39090	FlyBaseID:	FBgn0260859	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_038746.1	Gene:	Trappc3 / 27096	MGIID:	1351486	Length:	180	Species:	Mus musculus

Alignment Length:	180	Identity:	111/180 - (61%)
Similarity:	149/180 - (82%)	Gaps:	2/180 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRQASR-LDAKKVNSEFLTLTYGALVTQMLRDFENAEDVNKQLERIGYNMGMRLIEDFLARTSA 64
            |||||:| .::||::||..||||||||||:.:|:||.|||||||:|:|||:|:|||||||||::.
Mouse     1 MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDRMGYNIGVRLIEDFLARSNV 65

  Fly    65 PRCLEMRETADRIQQ-AFRIYLNIQPTISNWSPASDEFSLVFDSNPLTEFVELPPDLTNLRYSAI 128
            .||.:.|||||.|.: ||::||.|.|:|:|||||.|||||:.::|||.:|||||.:.:.|.||.:
Mouse    66 GRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSALIYSNL 130

  Fly   129 LSGCIRGALEMVQLEVQCWFVQDQLKGDNVTELRVKFVRRLEEVIPAGED 178
            |.|.:||||||||:.|:..||||.||||.|||:|::|:||:|:.:||||:
Mouse   131 LCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bet3	NP_648312.3	TRAPPC3_bet3	14..167	CDD:271345	96/153 (63%)
Trappc3	NP_038746.1	TRAPPC3_bet3	15..169	CDD:271345	96/153 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836190
Domainoid	1	1.000	190	1.000	Domainoid score	I3264
eggNOG	1	0.900	-	-		E1_KOG3330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6399
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3478
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54086
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002640
OrthoInspector	1	1.000	-	-		oto94988
orthoMCL	1	0.900	-	-		OOG6_102403
Panther	1	1.100	-	-	LDO	PTHR13048
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R136
SonicParanoid	1	1.000	-	-		X1739
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790