DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bet3 and TRAPPC3L

DIOPT Version :9

Sequence 1:	NP_648312.3	Gene:	Bet3 / 39090	FlyBaseID:	FBgn0260859	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001132916.1	Gene:	TRAPPC3L / 100128327	HGNCID:	21090	Length:	181	Species:	Homo sapiens

Alignment Length:	174	Identity:	83/174 - (47%)
Similarity:	118/174 - (67%)	Gaps:	3/174 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRQASRL-DAKKVNSEFLTLTYGALVTQMLRDFENAEDVNKQLERIGYNMGMRLIEDFLARTSA 64
            |||.|.|. :..|:|.:...|||||||.|:.:|:|..||||:.|:::||.:|.||:||||||:..
Human     1 MSRPAHRRPEYHKINKDLFVLTYGALVAQLCKDYEKDEDVNQYLDKMGYGIGTRLVEDFLARSCV 65

  Fly    65 PRCLEMRETADRIQQ-AFRIYLNIQPTISNWSPASDEFSLVFDSNPLTEFV-ELPPDLTNLRYSA 127
            .||....|..|.|.| ||::||.|.|:::..:.:.:||||:.:.|||.||| |||...::|.|..
Human    66 GRCHSYSEIIDIIAQVAFKMYLGITPSVTCNNSSKNEFSLILEKNPLVEFVEELPAGRSSLCYCN 130

  Fly   128 ILSGCIRGALEMVQLEVQCWFVQDQLKGDNVTELRVKFVRRLEE 171
            :|.|.||||||||.|.....|:||:||||:|||:.:.|:::.:|
Human   131 LLCGIIRGALEMVHLAADVTFLQDRLKGDSVTEIGITFLKKRDE 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bet3	NP_648312.3	TRAPPC3_bet3	14..167	CDD:271345	76/154 (49%)
TRAPPC3L	NP_001132916.1	TRAPPC3_bet3	15..170	CDD:271345	76/154 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146091
Domainoid	1	1.000	188	1.000	Domainoid score	I3316
eggNOG	1	0.900	-	-		E1_KOG3330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54086
OrthoDB	1	1.010	-	-		D1334804at2759
OrthoFinder	1	1.000	-	-		FOG0002640
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13048
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1739
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.820