DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MTF-1 and CG31365

DIOPT Version :9

Sequence 1:	NP_001097560.1	Gene:	MTF-1 / 39089	FlyBaseID:	FBgn0040305	Length:	1006	Species:	Drosophila melanogaster
Sequence 2:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	75/320 - (23%)
Similarity:	134/320 - (41%)	Gaps:	59/320 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 NEAANPPINCDN------DQGTGNSISRDST-----SNSPAYFTIETSYVDEYDPNEPDE----- 283
            |...:..::.||      :..:....::|||     .|....:.|:.....::...:|:|
  Fly   317 NMVGSDVVHTDNGEIYIINSASSEDQNQDSTPEFDQDNGITSYNIKEDGEIQFSGEKPEEIEDVV 381

  Fly   284 ----DEQLAHCIQPGVLHQDVDEEEVERQDENDQL---------MALAYESS---------DEAL 326
                .|:::...|....|::|...|.|:.|.::|.         :....|||         .:.:
  Fly   382 VFNLGEEISQEQQVFSFHENVIIVEKEQNDRDEQTPLKRKRSSELVFKQESSCPQPKTGRITDTV 446

  Fly   327 SRYRCNYENCYRSYSTIGNLRTHLKTHTGDY------SFKCPEDGCHKAFLTSYSLKIHVRVHTK 385
            ..::|:.  |..::.|...|..|..||....      :.|||  .|......:.|||.|:.:||.
  Fly   447 KSFQCHL--CPVAFPTQKLLTRHHNTHIKGLKSGKGGTLKCP--SCALQLSCASSLKRHMIIHTG 507

  Fly   386 VKPYECEVSGCDKAFNTRYRLHAHLRLHNG-ETFNCELCQKCFTTLSDLKKHM-RTHT-QERPYK 447
            :||::|  |.|:.:|:.|..|..|:..|.| :...|..|..||...|:|::|: |.|. ..|.:|
  Fly   508 LKPFKC--SECELSFSQREVLKRHMDTHTGVKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHK 570

  Fly   448 CPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNK 507
            |  ..|.::|.....|..|..||.|.. :.|::  |.:.|:...:::.|..| ..:::||
  Fly   571 C--HLCHRSFNHVSGLSRHLVTHAGVM-FSCKQ--CGRQFNDRSAVQRHVTT-MHKVKNK 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MTF-1	NP_001097560.1	zf-C2H2_aberr	329..471	CDD:293622	45/150 (30%)
		C2H2 Zn finger	331..353	CDD:275368	5/21 (24%)
		zf-H2C2_2	345..372	CDD:290200	8/32 (25%)
		C2H2 Zn finger	361..383	CDD:275368	7/21 (33%)
		zf-H2C2_2	375..402	CDD:290200	12/26 (46%)
		C2H2 Zn finger	391..413	CDD:275368	7/21 (33%)
		zf-C2H2	418..440	CDD:278523	8/22 (36%)
		C2H2 Zn finger	420..440	CDD:275368	8/20 (40%)
		zf-H2C2_2	432..458	CDD:290200	8/27 (30%)
		COG5048	442..>519	CDD:227381	17/66 (26%)
		C2H2 Zn finger	448..470	CDD:275368	5/21 (24%)
		zf-H2C2_2	462..489	CDD:290200	8/26 (31%)
		C2H2 Zn finger	478..500	CDD:275368	4/21 (19%)
		DUF3682	862..>931	CDD:289231
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	24/79 (30%)
		C2H2 Zn finger	485..505	CDD:275368	7/21 (33%)
		zf-H2C2_2	497..522	CDD:290200	12/26 (46%)
		C2H2 Zn finger	513..533	CDD:275368	7/21 (33%)
		zf-H2C2_2	526..550	CDD:290200	8/23 (35%)
		C2H2 Zn finger	541..562	CDD:275368	8/20 (40%)
		C2H2 Zn finger	571..591	CDD:275368	5/21 (24%)
		C2H2 Zn finger	598..617	CDD:275368	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24377
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100