DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MTF-1 and CG11906

DIOPT Version :9

Sequence 1:	NP_001097560.1	Gene:	MTF-1 / 39089	FlyBaseID:	FBgn0040305	Length:	1006	Species:	Drosophila melanogaster
Sequence 2:	NP_611402.2	Gene:	CG11906 / 37209	FlyBaseID:	FBgn0034425	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	69/341 - (20%)
Similarity:	116/341 - (34%)	Gaps:	101/341 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 DEYDPNEPDEDEQLAHCIQPGVLHQDVDEEEVERQDENDQLMALAYESSDEALSRYRCNYE---- 334
            |.||.:|.:|||               ::||:|...|..:      |..::|:...|.|:.
  Fly   350 DRYDMDEEEEDE---------------EDEEIESGGEELE------EGEEDAMYARRMNFTGDWI 393

  Fly   335 -NCYRS-----------YSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVK 387
             |..||           |...|.:.||:.|.. :|..              |.|.: ::...::|
  Fly   394 VNHSRSNSNSAGNLSLLYGDYGMVETHMTTDK-EYDL--------------YLLDL-LKTQVRLK 442

  Fly   388 PYECEVSGCDKAFNTRYRL--HAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERP-YKCP 449
            .:.|....|....:|...|  |.::.......|.|..|...||:...|..||  |.|.|. |.|.
  Fly   443 SFTCFTPDCGYQTDTLVALMKHDYMEHWKMSWFYCHKCGDVFTSKVFLDYHM--HLQNRGLYICH 505

  Fly   450 EDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSH--KKTHQRQLQNKGRKKR 512
            :  |.:.|...|.|..|.:.|.....|.|  :.|:..|.:...|.:|  |..|
  Fly   506 K--CREEFELQHQLDRHFQLHRKGINYHC--NFCRLEFLSEAKLLAHCKKLGH------------ 554

  Fly   513 PLKTQQTKCSDQEQKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHL 577
                                ...:|..|..|: .::::|    |....|:|...::::...::..
  Fly   555 --------------------SPNDEPLISIDR-SLSIVN----CHVPRSSDYSRIVKSYEEREFY 594

  Fly   578 SNVFILQGNEPLILPE 593
            .....:...:|:.||:
  Fly   595 IPRIPMPSTQPMHLPQ 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MTF-1	NP_001097560.1	zf-C2H2_aberr	329..471	CDD:293622	37/160 (23%)
		C2H2 Zn finger	331..353	CDD:275368	8/37 (22%)
		zf-H2C2_2	345..372	CDD:290200	4/26 (15%)
		C2H2 Zn finger	361..383	CDD:275368	2/21 (10%)
		zf-H2C2_2	375..402	CDD:290200	4/26 (15%)
		C2H2 Zn finger	391..413	CDD:275368	5/23 (22%)
		zf-C2H2	418..440	CDD:278523	8/21 (38%)
		C2H2 Zn finger	420..440	CDD:275368	7/19 (37%)
		zf-H2C2_2	432..458	CDD:290200	9/26 (35%)
		COG5048	442..>519	CDD:227381	18/79 (23%)
		C2H2 Zn finger	448..470	CDD:275368	6/21 (29%)
		zf-H2C2_2	462..489	CDD:290200	7/26 (27%)
		C2H2 Zn finger	478..500	CDD:275368	6/23 (26%)
		DUF3682	862..>931	CDD:289231
CG11906	NP_611402.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457146
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930