DRSC/TRiP Functional Genomics Resources

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Protein Alignment MTF-1 and sna

DIOPT Version :10

Sequence 1:NP_001097560.1 Gene:MTF-1 / 39089 FlyBaseID:FBgn0040305 Length:1006 Species:Drosophila melanogaster
Sequence 2:NP_476732.1 Gene:sna / 34908 FlyBaseID:FBgn0003448 Length:390 Species:Drosophila melanogaster


Alignment Length:501 Identity:119/501 - (23%)
Similarity:173/501 - (34%) Gaps:198/501 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 DQEKQHQQQQQHYFHSEWKTTANSHGNSLSDSRDYDTNSSRNSLSGSPPVTSNCSSSGSLDFDRP 67
            |:|.|..||.:                   ..|||..|.|:.      |..::.|||.|.     
  Fly    51 DEETQDYQQPE-------------------PKRDYVLNLSKT------PERNSSSSSNSC----- 85

  Fly    68 LAQLLEPKLEADGLGIIHGDNYSIYGSQTAESTSGEQQVLNLGLTLDTGDAQATYGDLFGAQDQL 132
               ||.|.:||        .:|.            ..::...|||.             |.....
  Fly    86 ---LLSPPVEA--------QDYL------------PTEIHMRGLTA-------------GTTGYT 114

  Fly   133 TASQT--HGHSQVVVSAAADNAFSLADQLTPLPITVIPITYHHTTENLSSSHSEVPLIASLSDIT 195
            ||:.|  :......|.||..|           ||:.:..:|.   .:|::..|....:||...: 
  Fly   115 TATPTTINPFQSAFVMAAGCN-----------PISALWSSYQ---PHLAAFPSPASSMASPQSV- 164

  Fly   196 AQVFNLDDICFTLEYQFENQRLVQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGNSISRDSTS 260
                          |.::     |:.||        |||.          :|..||         
  Fly   165 --------------YSYQ-----QMTPP--------SSPG----------SDLETG--------- 183

  Fly   261 NSPAYFTIETSYVDEYDPNEPDEDEQLAHCIQ-PGVLHQDVDEEEVERQDENDQLMALAYESSDE 324
                              :|| ||..:.:.|. |.:.|.            .|:..:.:..:|..
  Fly   184 ------------------SEP-EDLSVRNDIPLPALFHL------------FDEAKSSSSGASVS 217

  Fly   325 ALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPY 389
            :.|.|.........|.|...|       |..:|.|||  |.|.|.:.||..|..|.:.|      
  Fly   218 SSSGYSYTPAMSASSASVAAN-------HAKNYRFKC--DECQKMYSTSMGLSKHRQFH------ 267

  Fly   390 ECEVSGCDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCG 454
             |..:.|::               ..:|.:||.|.|.:||:..||.|:||||  .|.|||  .||
  Fly   268 -CPAAECNQ---------------EKKTHSCEECGKLYTTIGALKMHIRTHT--LPCKCP--ICG 312

  Fly   455 KAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTH 500
            |||:....|:.|.||||||||:.|.:  |.:||:...:|::|::||
  Fly   313 KAFSRPWLLQGHIRTHTGEKPFQCPD--CPRSFADRSNLRAHQQTH 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MTF-1NP_001097560.1 COG5048 <319..498 CDD:227381 60/178 (34%)
C2H2 Zn finger 331..353 CDD:275368 3/21 (14%)
C2H2 Zn finger 361..383 CDD:275368 8/21 (38%)
C2H2 Zn finger 391..413 CDD:275368 2/21 (10%)
C2H2 Zn finger 420..440 CDD:275368 10/19 (53%)
C2H2 Zn finger 448..470 CDD:275368 10/21 (48%)
C2H2 Zn finger 478..500 CDD:275368 6/21 (29%)
PRK14954 <863..>941 CDD:184918
snaNP_476732.1 SFP1 <245..303 CDD:227516 25/81 (31%)
C2H2 Zn finger 247..267 CDD:275368 8/21 (38%)
C2H2 Zn finger 282..302 CDD:275368 10/19 (53%)
zf-C2H2 306..328 CDD:395048 11/23 (48%)
C2H2 Zn finger 308..328 CDD:275368 10/21 (48%)
zf-H2C2_2 321..344 CDD:463886 13/24 (54%)
zf-C2H2 334..356 CDD:395048 6/23 (26%)
C2H2 Zn finger 336..356 CDD:275368 6/21 (29%)
zf-H2C2_2 348..373 CDD:463886 4/9 (44%)
C2H2 Zn finger 364..380 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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