DRSC/TRiP Functional Genomics Resources

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Protein Alignment MTF-1 and esg

DIOPT Version :10

Sequence 1:NP_001097560.1 Gene:MTF-1 / 39089 FlyBaseID:FBgn0040305 Length:1006 Species:Drosophila melanogaster
Sequence 2:NP_476600.1 Gene:esg / 34903 FlyBaseID:FBgn0287768 Length:470 Species:Drosophila melanogaster


Alignment Length:508 Identity:114/508 - (22%)
Similarity:183/508 - (36%) Gaps:162/508 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 SHGNSLSDSRDYDTNSSRNSLSGSPPVTSNCSSSGSLDFDRPLAQLLEPK--LEADGLGIIHGDN 88
            :|.|:.::.:|.                  |.....:..:.|..:|:...  .|.:|:.:.|.|:
  Fly    32 NHSNTPNEPQDL------------------CVKKMEILEENPSEELINVSDCCEDEGVDVDHTDD 78

  Fly    89 YSIYGSQTAESTSGEQQVLNLGLTLDTGDAQATYGDLFGAQDQLTASQTHGHSQVVVSAAADNAF 153
                     |....|.:.:::.:..|....||.                     .:.:|||..|.
  Fly    79 ---------EHIEEEDEDVDVDVDSDPNQTQAA---------------------ALAAAAAVAAA 113

  Fly   154 SLADQLTPLPITVIPITYHHTTENLSSSHSEVPLIASLSDITAQVFNLDDICFTLEYQFENQRLV 218
            :.|..:.|.|      ||.....|  :.|        :|..||:.           |:..||:..
  Fly   114 AAASVVVPTP------TYPKYPWN--NFH--------MSPYTAEF-----------YRTINQQGH 151

  Fly   219 QVQPPTVVSLSMVSSPNE---AANPPINCDNDQGTGNSISRDSTSN------------------- 261
            |:. |....|...|||::   :.:||.: ....|..:|:|....|.                   
  Fly   152 QIL-PLRGDLIAPSSPSDSLGSLSPPPH-HYLHGRASSVSPPMRSEIIHRPIGVRQHRFLPYPQM 214

  Fly   262 -------------------SPAYFTIETSY--VDEYDPNEP-----DEDEQLAH--------CIQ 292
                               ||||  .|.||  :....|...     .||..|.|        ..|
  Fly   215 PGYPSLGGYTHTHHHHAPISPAY--SENSYYSMRSMTPESSCSSSLPEDLSLKHKNLNLNLNTSQ 277

  Fly   293 PGVLHQDVDEEEVERQDENDQLMALAYESSDE-ALSRYRCNYENCYRSYSTIGNLRTHLKTH--- 353
            ||      ::...:..|.:.:.|..|....|: ...||:|  .:|.:||||...|..|.:.|   
  Fly   278 PG------EQAAAKTGDMSPETMPNASAKKDKNQPPRYQC--PDCQKSYSTFSGLTKHQQFHCPA 334

  Fly   354 -TGDY---SFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRYRLHAHLRLHN 414
             .|:.   ||.|.:  |.|.:::..:||:|:|.||  .|.:|.:  |.|||:..:.|..|:|.|.
  Fly   335 AEGNQVKKSFSCKD--CDKTYVSLGALKMHIRTHT--LPCKCNL--CGKAFSRPWLLQGHIRTHT 393

  Fly   415 GE-TFNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTH 466
            || .|:|:.|.:.|...|:|:.|::||:..:.|.|  ..|.|.|:....|..|
  Fly   394 GEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSC--TSCSKTFSRMSLLTKH 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MTF-1NP_001097560.1 COG5048 <319..498 CDD:227381 52/157 (33%)
C2H2 Zn finger 331..353 CDD:275368 8/21 (38%)
C2H2 Zn finger 361..383 CDD:275368 7/21 (33%)
C2H2 Zn finger 391..413 CDD:275368 8/21 (38%)
C2H2 Zn finger 420..440 CDD:275368 6/19 (32%)
C2H2 Zn finger 448..470 CDD:275368 6/19 (32%)
C2H2 Zn finger 478..500 CDD:275368
PRK14954 <863..>941 CDD:184918
esgNP_476600.1 KREPA <278..>329 CDD:483960 16/58 (28%)
zf-C2H2 309..331 CDD:395048 9/23 (39%)
C2H2 Zn finger 311..331 CDD:275370 8/21 (38%)
zf-C2H2 344..366 CDD:395048 8/23 (35%)
C2H2 Zn finger 346..366 CDD:275368 7/21 (33%)
zf-C2H2 370..392 CDD:395048 8/23 (35%)
C2H2 Zn finger 372..392 CDD:275368 8/21 (38%)
zf-H2C2_2 385..408 CDD:463886 9/22 (41%)
zf-C2H2 398..420 CDD:395048 7/21 (33%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
C2H2 Zn finger 428..444 CDD:275368 5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

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