DRSC/TRiP Functional Genomics Resources

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Protein Alignment MTF-1 and Glis2

DIOPT Version :9

Sequence 1:NP_001097560.1 Gene:MTF-1 / 39089 FlyBaseID:FBgn0040305 Length:1006 Species:Drosophila melanogaster
Sequence 2:XP_038941774.1 Gene:Glis2 / 302946 RGDID:1309177 Length:522 Species:Rattus norvegicus


Alignment Length:495 Identity:109/495 - (22%)
Similarity:162/495 - (32%) Gaps:155/495 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   206 FTLEYQFENQRLVQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGN-SISRDSTSNSPAYFTIE 269
            |.|..:|..:...:.....:|.||:        :||...|:..|:.: |..|....:.|...|..
  Rat    59 FLLNPKFPEKLDGRFSAAPLVDLSL--------SPPSGLDSPNGSSSLSPERQGNGDLPPLPTAV 115

  Fly   270 TSYVDEYDPNEPDEDEQLAHCIQPGVLHQDVDEEEVERQDENDQLMALAY--ESSDEALS----- 327
            ......|....|...:........|.||                |.|.::  ...|:.||     
  Rat   116 DFQPLRYLDGVPSSFQFFLPLGSGGALH----------------LPASSFLTPPKDKCLSPELPL 164

  Fly   328 --RYRCNYENCYRSYSTIGNLRTHLKTH----TGDYSFKCPEDGC--H-KAFLTS-YSLKIHVRV 382
              :..|.:..|.:.:..:.:|..|:..|    ..|..:.|..:||  | :.|..| |.:.||:|.
  Rat   165 AKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNASRYKMLIHIRT 229

  Fly   383 HTKVKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCELCQKCFTTLSDLKKHMRTHTQERPYK 447
            ||..||:.|..                             |.|.|:.|.:||.|.|:||.|:||.
  Rat   230 HTNEKPHRCPT-----------------------------CNKSFSRLENLKIHNRSHTGEKPYV 265

  Fly   448 CPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNKGRKKR 512
            ||.:.|.|.::.|.....|.|||..:|||.|:...|.|.::...||:.|.|.|            
  Rat   266 CPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAH------------ 318

  Fly   513 PLKTQQTKCSDQEQKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHL 577
                                    ..|:..:|.|:..|.|                   .|:   
  Rat   319 ------------------------GHFVSHEQQELLQLRP-------------------PPK--- 337

  Fly   578 SNVFILQGNEPLILPETSQAYQLSY--AAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALPTEM 640
                     .||..|::.     ||  .|:..||:|    ..|...|.:|..||..|...|....
  Rat   338 ---------PPLPTPDSG-----SYVSGAQIIIPNP----AALFGGPSLPGLPLPLAPGPLDLSA 384

  Fly   641 PSFVNLKPTFGNAVSGNMGDPQP-ETMDVDPTVETSLPTP 679
            .:..|     |....|.||...| ..:.::......||:|
  Rat   385 LACGN-----GGGGGGGMGPGLPGSVLPLNLAKNPLLPSP 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MTF-1NP_001097560.1 zf-C2H2_aberr 329..471 CDD:293622 42/149 (28%)
C2H2 Zn finger 331..353 CDD:275368 4/21 (19%)
zf-H2C2_2 345..372 CDD:290200 9/33 (27%)
C2H2 Zn finger 361..383 CDD:275368 10/25 (40%)
zf-H2C2_2 375..402 CDD:290200 8/26 (31%)
C2H2 Zn finger 391..413 CDD:275368 1/21 (5%)
zf-C2H2 418..440 CDD:278523 8/21 (38%)
C2H2 Zn finger 420..440 CDD:275368 8/19 (42%)
zf-H2C2_2 432..458 CDD:290200 13/25 (52%)
COG5048 442..>519 CDD:227381 23/76 (30%)
C2H2 Zn finger 448..470 CDD:275368 7/21 (33%)
zf-H2C2_2 462..489 CDD:290200 10/26 (38%)
C2H2 Zn finger 478..500 CDD:275368 7/21 (33%)
DUF3682 862..>931 CDD:289231
Glis2XP_038941774.1 C2H2 Zn finger 213..230 CDD:275368 6/16 (38%)
COG5048 234..>328 CDD:227381 38/158 (24%)
C2H2 Zn finger 238..258 CDD:275368 9/48 (19%)
C2H2 Zn finger 266..288 CDD:275368 7/21 (33%)
C2H2 Zn finger 296..318 CDD:275368 7/21 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 136 1.000 Inparanoid score I4459
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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