Protein Alignment MTF-1 and mtf1

DIOPT Version :10

• Sequence 1: NP_001097560.1
• Gene: MTF-1 / 39089
• FlyBaseID: FBgn0040305
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: XP_021322285.1
• Gene: mtf1 / 195821
• ZFINID: ZDB-GENE-020424-1
• Length: 749
• Species: Danio rerio
• Alignment Length: 751
• Identity: 226/751 - (30%)
• Similarity: 313/751 - (41%)
• Gaps: 207/751 - (27%)

  Fly   243 NCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPNEPDEDEQ----------------LAHCI 291
            |.|.|   ||.||..|:|:...|  ..|:.:.|.||...||:.:                ||...
Zfish    63 NFDKD---GNMISGPSSSSGTVY--DRTTVLIEQDPIRLDEEGEEDGMTFLPEGEGDEGSLAFMG 122

  Fly   292 QP-----GVLHQDVDEEEVE-----------RQDENDQLM--ALAYESSDEALSRYRCNYENCYR 338
            .|     |.:|..:..::::           |..|...|.  :...|:....:.||:|.:|.|.|
Zfish   123 DPDGMSQGYIHHTISPDQIQFIINPGSTPMPRNIEGATLTLHSECPETKQREVKRYQCLFEGCTR 187

  Fly   339 SYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTR 403
            :|||.||||||.|||.|:|:|.|.:.||.||||||||||||||||||.||:||:|.||:|||||.
Zfish   188 TYSTAGNLRTHQKTHRGEYTFVCNQQGCGKAFLTSYSLKIHVRVHTKEKPFECDVQGCEKAFNTL 252

  Fly   404 YRLHAHLRLHNGETFNCEL--CQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTH 466
            |||.||.|||.|:|||||.  |.|.|||||||:||:||||.|:|::|..|.|||||.||||||||
Zfish   253 YRLKAHQRLHTGKTFNCESEGCTKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTH 317

  Fly   467 RRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQR----------------------------- 502
            .||||||||:.|..|.|:|:||:.:|||||.:.|.:
Zfish   318 VRTHTGEKPFFCPSDGCEKTFSSQYSLKSHIRGHDKGPSFTVSSHPLSEDANHSLCLSDLSLIST 382

  Fly   503 --QLQNKGRKK-------RPLKTQQTKCSDQE----QKDPQQEEQEEEEFIKEDQPEMTLLNPGS 554
              :||.....:       .|::..:......|    :.||:..|...|.|..|..|:....:..:
Zfish   383 DSELQENHNSQGLDLNSVTPIRIFELMFQSPENSVSEDDPKPTESLAESFGLEPSPQTAPADAST 447

  Fly   555 H----------CSETTSTDSGVVLQTLTPQDHLSNVFILQGNEPLILPETSQAYQLSYAAEEEIP 609
            |          ||.:.|.       |...||         ...|   |.|.||...:.::..:..
Zfish   448 HPAFPQPPPSTCSSSCSI-------TAPAQD---------AQTP---PTTQQAPPPAVSSSSQTS 493

  Fly   610 S-----PWIDAGVLVSKPIIPMAPLTDACVALPTEMPSFVNLKPTFGN------AVSGNMGDPQP 663
            |     |.......||.|..|.| .....:|.|...||..::......      ||:..:....|
Zfish   494 SFPSAPPSSSQPAEVSSPSAPSA-TQHYMMAQPVSSPSAASVSSVPAGTAEVTAAVTHTVPLAAP 557

  Fly   664 ETMDVDPTVETSLPTPTLELNQPNIEELLKQ--DSFENEEDM--ETESLLNDILMTIDNNSALLQ 724
            .|:.:.||:...   |:|.::..|::.:|..  .:.:|.|..  :.|.:.....:.:..||.
Zfish   558 PTISIAPTLGLQ---PSLVMSDQNLQWILSSAASAQQNPEQQGPKVEKVFFTTAIPVGGNSG--- 616

  Fly   725 ATLQQASQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKC-DQTKSCHGGDCGAAAAQQT 788
            ..:||.        ||       :.|.:  |......|.| :|.| |..|     |...:::|..
Zfish   617 NAVQQI--------GL-------SLPVI--IIKQEESCQC-HCACRDSAK-----DKSTSSSQDK 658

  Fly   789 TRTGAP-------------------------------TTTTTTTTMNSSGGKRICGSVVPTKKVS 822
            |:..:|                               ...|...|.|.           ||..:.
Zfish   659 TKNTSPPPPPAPPPPPPALPKEPPSCCPSKPHTQPQQDLPTAPLTPNP-----------PTDALG 712

  Fly   823 KRET------EMNQNIEDVALLLQNLASMSSGGSSG 852
            ..:.      |...||| ..|::.:..||:.||.||
Zfish   713 SMDVSDLLSPETTANIE-ALLMVADGFSMADGGGSG 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTF-1	NP_001097560.1	COG5048	<319..498	CDD:227381	120/180 (67%)
		C2H2 Zn finger	331..353	CDD:275368	14/21 (67%)
		C2H2 Zn finger	361..383	CDD:275368	17/21 (81%)
		C2H2 Zn finger	391..413	CDD:275368	15/21 (71%)
		C2H2 Zn finger	420..440	CDD:275368	14/21 (67%)
		C2H2 Zn finger	448..470	CDD:275368	16/21 (76%)
		C2H2 Zn finger	478..500	CDD:275368	11/21 (52%)
		PRK14954	<863..>941	CDD:184918
mtf1	XP_021322285.1	C2H2 Zn finger	183..202	CDD:275368	13/18 (72%)
		COG5048	<185..349	CDD:227381	115/163 (71%)
		C2H2 Zn finger	210..232	CDD:275368	17/21 (81%)
		C2H2 Zn finger	240..262	CDD:275368	15/21 (71%)
		C2H2 Zn finger	272..291	CDD:275368	12/18 (67%)
		C2H2 Zn finger	299..321	CDD:275368	16/21 (76%)
		COG5048	302..>431	CDD:227381	41/128 (32%)
		C2H2 Zn finger	329..351	CDD:275368	11/21 (52%)