Protein Alignment MTF-1 and Mtf1

DIOPT Version :10

• Sequence 1: NP_001097560.1
• Gene: MTF-1 / 39089
• FlyBaseID: FBgn0040305
• Length: 1006
• Species: Drosophila melanogaster
• Sequence 2: NP_032662.3
• Gene: Mtf1 / 17764
• MGIID: 101786
• Length: 675
• Species: Mus musculus
• Alignment Length: 648
• Identity: 209/648 - (32%)
• Similarity: 291/648 - (44%)
• Gaps: 165/648 - (25%)

  Fly   245 DNDQGTGNSISRDSTSNSPAYFTIETS---YVDEYDPNEPDEDEQLAHCIQPGVLHQDVD--EEE 304
            :.|.||......|.....|..|.:|..   .:|:    |......:.|.|.|..:|..::  ...
Mouse    52 EQDPGTLEDDEDDGQCGEPLPFLVEGEEGFLIDQ----EAMSQGYVQHIISPDQIHLTINPGSTP 112

  Fly   305 VERQDEND--QLMALAYESSDEALSRYRCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCH 367
            :.|..|..  .|.:...|:..:.:.||:|.:|.|.|:|||.||||||.|||.|:|:|.|.::||.
Mouse   113 MPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCG 177

  Fly   368 KAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCEL--CQKCFTTL 430
            |||||||||:||||||||.||:||:|.||:|||||.|||.||.|||.|:|||||.  |.|.||||
Mouse   178 KAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTL 242

  Fly   431 SDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKS 495
            |||:||:||||.|:|::|..|.|||||.||||||||.||||||:|:.|..:.|:|:|||.:||||
Mouse   243 SDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKS 307

  Fly   496 HKKTHQRQLQNKGRKKRPLKTQQTKCSDQEQKDPQQEEQEEEE---FIKEDQPEMTLLNPGSHCS 557
            |.|.|    .|||.....|              ||....|:..   ::.    |:.||:..|...
Mouse   308 HMKGH----DNKGTAYSAL--------------PQHNGSEDTNHSLYLS----ELGLLSTDSELQ 350

  Fly   558 ETTSTDSGVVLQTLTP----------------QD------------------------------H 576
            |.:|:.....|.|::|                ||                              .
Mouse   351 ENSSSTQDQDLSTISPAIIFESMFQNSDDPGIQDDPLQTAALIDSFNGDAESVIDVPPPAGNSAS 415

  Fly   577 LSNVFILQ----------------------------------GNEPLIL--PETSQAYQLSYAA- 604
            ||...:||                                  |:.|.:|  ||....:...:||
Mouse   416 LSLPLVLQSGISEPPQPLLPATAPSAPPPAPSLGPGSQPAAFGSPPALLQPPEVPVPHSTQFAAN 480

  Fly   605 -EEEIPSPWIDAGVLV-SKPIIPMAPLTDA----CVALP------TE-MPSFVNLKPTFGNAVSG 656
             :|.:|.|......:| ...::..||.:.|    .||.|      || :|:.|...|...|:|..
Mouse   481 HQEFLPHPQAPPQTIVPGLSVVAGAPASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLT 545

  Fly   657 NMGDPQPETMDVDPTVETSLPTPTLELNQPNIEELLK--QDSFENEEDMETESLLNDILMTIDNN 719
            |  :|   |:.:.||..|::...:|.:.:.|::.:|.  ..|.:|:|.::..|.:..:..
Mouse   546 N--NP---TITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEQVYF----- 600

  Fly   720 SALLQATLQQASQVP---SDASGLVELDIRDNKPTLKQITADAGICNCTNCKC-DQTKSCHGG 778
                      |:.||   ...|.:.::.:......:||..|    |.| .|.| |..|....|
Mouse   601 ----------ATAVPVASGTGSSVQQIGLSVPVIIIKQEEA----CQC-QCACRDSAKERAAG 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTF-1	NP_001097560.1	COG5048	<319..498	CDD:227381	118/180 (66%)
		C2H2 Zn finger	331..353	CDD:275368	14/21 (67%)
		C2H2 Zn finger	361..383	CDD:275368	16/21 (76%)
		C2H2 Zn finger	391..413	CDD:275368	15/21 (71%)
		C2H2 Zn finger	420..440	CDD:275368	14/21 (67%)
		C2H2 Zn finger	448..470	CDD:275368	16/21 (76%)
		C2H2 Zn finger	478..500	CDD:275368	12/21 (57%)
		PRK14954	<863..>941	CDD:184918
Mtf1	NP_032662.3	COG5048	<92..308	CDD:227381	123/215 (57%)
		Nuclear localization signal. /evidence=ECO:0000255	132..137		0/4 (0%)
		C2H2 Zn finger	141..163	CDD:275368	14/21 (67%)
		C2H2 Zn finger	171..193	CDD:275368	16/21 (76%)
		C2H2 Zn finger	201..223	CDD:275368	15/21 (71%)
		C2H2 Zn finger	235..252	CDD:275368	12/16 (75%)
		C2H2 Zn finger	260..282	CDD:275368	16/21 (76%)
		C2H2 Zn finger	290..312	CDD:275368	12/21 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	427..464		2/36 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..675		1/4 (25%)