DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aay and psph

DIOPT Version :9

Sequence 1:	NP_524001.2	Gene:	aay / 39085	FlyBaseID:	FBgn0023129	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001028271.1	Gene:	psph / 606663	ZFINID:	ZDB-GENE-050809-127	Length:	226	Species:	Danio rerio

Alignment Length:	211	Identity:	105/211 - (49%)
Similarity:	159/211 - (75%)	Gaps:	1/211 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 VIQQSQIVCFDVDSTVICEEGIDELAEYCGKGSEVARVTKEAMGGAMTFQDALKIRLNIIRPTQQ 121
            :::::..||||||||||.||||||||::||.|..|..:|::||||:|:||.||..||:||:.:::
Zfish    10 LLRRADAVCFDVDSTVIREEGIDELAKFCGVGDAVTEMTRKAMGGSMSFQTALSERLSIIKCSRE 74

  Fly   122 QVRDFIQERPSTLSKNVKRFVSHLKAEGKQVYLISGGFDCLIAPVANELGIPLKNVYANKMLFDY 186
            ||...|.:.|..|:..::..|..|:..|.||:|:||||.|::..||::|.|||::||||::.|.:
Zfish    75 QVNKLITDHPPQLTPGIRELVQKLQQRGVQVFLVSGGFRCIVEHVASQLSIPLQHVYANRLKFYF 139

  Fly   187 LGEYDSFDINQPTSRSGGKAEAIALIRKENSDDSLITMIGDGATDLEAVPPANYFIGFGGNVVRP 251
            .|||..||.:|||::||||...|:::::::...::: |||||||||||.|||:.||||||||:||
Zfish   140 NGEYAGFDESQPTAQSGGKGRVISMLKEKHGFQNIL-MIGDGATDLEACPPASAFIGFGGNVLRP 203

  Fly   252 EVYRRAQYYVTDFEQL 267
            :|..::.:||:.|.:|
Zfish   204 QVKEKSSWYVSSFSEL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aay	NP_524001.2	HAD_like	54..268	CDD:304363	105/211 (50%)
aay	NP_524001.2	Hydrolase	63..234	CDD:279092	85/170 (50%)
psph	NP_001028271.1	PLN02954	9..224	CDD:215514	105/211 (50%)
psph	NP_001028271.1	Hydrolase	15..186	CDD:279092	85/171 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581475
Domainoid	1	1.000	180	1.000	Domainoid score	I3475
eggNOG	1	0.900	-	-		E1_COG0560
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31245
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3509
OMA	1	1.010	-	-		QHG57974
OrthoDB	1	1.010	-	-		D1009123at2759
OrthoFinder	1	1.000	-	-		FOG0003213
OrthoInspector	1	1.000	-	-		oto38995
orthoMCL	1	0.900	-	-		OOG6_101696
Panther	1	1.100	-	-	LDO	PTHR43344
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1319
SonicParanoid	1	1.000	-	-		X4217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800