DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment aay and Y62E10A.13

DIOPT Version :9

Sequence 1:	NP_524001.2	Gene:	aay / 39085	FlyBaseID:	FBgn0023129	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001293893.1	Gene:	Y62E10A.13 / 178304	WormBaseID:	WBGene00013379	Length:	287	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	115/248 - (46%)
Similarity:	152/248 - (61%)	Gaps:	18/248 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 AKTTVASAI-----TPP------KQPQLAAKVIQQSQIVCFDVDSTVICEEGIDELAEYCGKGSE 90
            |..|.||||     |.|      ...:...:|.:::..|||||||||..:|||||||.|.|.|..
Worm    27 ALPTTASAIPRSISTSPGETISKNHEEEVKRVWRKADAVCFDVDSTVCQDEGIDELAAYLGVGEA 91

  Fly    91 VARVTKEAMGGAMTF--QDALKIRLNIIRPTQQQVRDFIQERPSTLSKNVKRFVSHLKAEGKQVY 153
            ||.||:.||.|...|  :|||..||.:::|..:|:..|:......|:..::..||.|.|.|..||
Worm    92 VANVTRTAMNGNARFRYRDALAARLQVMKPNHEQLEQFVNISKPKLTVGIRELVSRLHARGTHVY 156

  Fly   154 LISGGFDCLIAPVANELGIPLKNVYANKMLFDYLGEYDSFDINQPTSRSG----GKAEAIALIRK 214
            |:||||..||.|||..|||....:|||::|||..|:|..||.::.||.||    ||...|||::|
Worm   157 LVSGGFRRLILPVAELLGIEKSRIYANEILFDKFGKYHGFDTSELTSDSGSKETGKPAVIALLKK 221

  Fly   215 ENSDDSLITMIGDGATDLEAVPPANYFIGFGGNVVRPEVYRRAQYYVTDFEQL 267
            ..:..::: |:||||||:||.|||:.||||||||:|..|..||::|||||:.|
Worm   222 MYNYKTVV-MVGDGATDVEASPPADAFIGFGGNVIREGVKARAKWYVTDFDVL 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aay	NP_524001.2	HAD_like	54..268	CDD:304363	107/220 (49%)
aay	NP_524001.2	Hydrolase	63..234	CDD:279092	83/176 (47%)
Y62E10A.13	NP_001293893.1	PLN02954	53..278	CDD:215514	107/222 (48%)
Y62E10A.13	NP_001293893.1	Hydrolase	63..240	CDD:279092	83/177 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159651
Domainoid	1	1.000	152	1.000	Domainoid score	I2646
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31245
Inparanoid	1	1.050	196	1.000	Inparanoid score	I2515
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57974
OrthoDB	1	1.010	-	-		D1009123at2759
OrthoFinder	1	1.000	-	-		FOG0003213
OrthoInspector	1	1.000	-	-		oto17801
orthoMCL	1	0.900	-	-		OOG6_101696
Panther	1	1.100	-	-	LDO	PTHR43344
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1319
SonicParanoid	1	1.000	-	-		X4217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940