DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cpsf5 and cfim-1

DIOPT Version :9

Sequence 1:	NP_001036597.1	Gene:	Cpsf5 / 39083	FlyBaseID:	FBgn0035987	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_492334.1	Gene:	cfim-1 / 172657	WormBaseID:	WBGene00009668	Length:	227	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	138/193 - (71%)
Similarity:	163/193 - (84%)	Gaps:	0/193 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NRTINLYPLTNYTFGTKEPLFEKDPSVPSRFQRMREEFDRIGMRRSVEGVLLVHEHGLPHVLLLQ 108
            |||||:|||||||||||:...|||.|||.||:||::|::.:|||||||.||:||||.|||:||||
Worm    31 NRTINVYPLTNYTFGTKDAQAEKDKSVPERFKRMKDEYEVMGMRRSVEAVLIVHEHSLPHILLLQ 95

  Fly   109 LGTTFFKLPGGELNAGEDEVEGLKRLLSETLGRQDGVKQEWIVEDTIGNWWRPNFEPPQYPYIPP 173
            :||||:|||||||..||||:.|:.|||:|||||.||...||.:||.|||||||||:||:|||||.
Worm    96 IGTTFYKLPGGELELGEDEISGVTRLLNETLGRTDGETNEWTIEDEIGNWWRPNFDPPRYPYIPA 160

  Fly   174 HITKPKEHKRLFLVQLHEKALFAVPKNYKLVAAPLFELYDNSQGYGPIISSLPQALCRFNFIY 236
            |:||||||.:|.||||..|:.|.||||:|||||||||||||:..|||:|||||..|.|||||:
Worm   161 HVTKPKEHTKLLLVQLPSKSTFCVPKNFKLVAAPLFELYDNAAAYGPLISSLPTTLSRFNFIF 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf5	NP_001036597.1	NUDIX_2	45..232	CDD:404710	132/186 (71%)
cfim-1	NP_492334.1	NUDIX_2	32..219	CDD:372769	132/186 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162512
Domainoid	1	1.000	295	1.000	Domainoid score	I803
eggNOG	1	0.900	-	-		E1_KOG1689
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5090
Inparanoid	1	1.050	306	1.000	Inparanoid score	I1585
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54579
OrthoDB	1	1.010	-	-		D1194206at2759
OrthoFinder	1	1.000	-	-		FOG0006316
OrthoInspector	1	1.000	-	-		oto19059
orthoMCL	1	0.900	-	-		OOG6_102904
Panther	1	1.100	-	-	LDO	PTHR13047
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4135
SonicParanoid	1	1.000	-	-		X4023
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800