Protein Alignment CG4022 and LOC5667296

DIOPT Version :10

• Sequence 1: NP_648307.1
• Gene: CG4022 / 39082
• FlyBaseID: FBgn0035986
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_061497138.1
• Gene: LOC5667296 / 5667296
• VectorBaseID: AGAMI1_014608
• Length: 657
• Species: Anopheles gambiae
• Alignment Length: 582
• Identity: 197/582 - (33%)
• Similarity: 261/582 - (44%)
• Gaps: 183/582 - (31%)

  Fly    53 ETQLQMHQDPQQQQE---LEGNSNNGITGLGLSLMNSSPPPHSYRHSRAYRHFKNPPQPHMCIRT 114
            :.|...||..||||:   ::|..||.              ||  |.|||.|.|||||||||||:.
Mosquito    49 QNQQPNHQQQQQQQQDLTIDGIPNNF--------------PH--RRSRASRTFKNPPQPHMCIKE 97

  Fly   115 TTEAGEELFINVLSWTRIVIPQEPSDPIPLYGGMRV---PPGSPRSPPIVFAVMANPEVLKDSGR 176
            .|..|:|:||||||||||..|..|..||||||||:|   |||||::||:|:||||:|||||.:||
Mosquito    98 RTLDGKEVFINVLSWTRIANPDNPDAPIPLYGGMKVGKIPPGSPKAPPLVYAVMASPEVLKKAGR 162

  Fly   177 HSKDPEERRAMVELMCDFVEAMNPGVKLVRNAVILKDRDISGELKDVWNAVQAQRDRERE----- 236
            ...|..||..:|:|||:|||||||.:.|.|...||||||:||||||||:||||.||:.|.
Mosquito   163 KCPDTPERMNLVDLMCEFVEAMNPSLHLSRKPEILKDRDLSGELKDVWSAVQACRDKGRSDNGPP 227

  Fly   237 -----------------EQMMQQ--RQQQHYQNITTQQMF---PKSPDASR--AASAGAAVNEAS 277
                             ||.:||  .||||.|.:..||.:   |.:||...  ..|.|....:..
Mosquito   228 ENLVVYTEFGPDSAPSYEQTIQQHHHQQQHQQQLQYQQQYDQLPNTPDQQGRFPLSTGQQQQQHH 292

  Fly   278 SPPAHLSEPLLVEQGNGNGNGITLAVFAQQLDNKVASEQGEQQEQS-----------------PV 325
            .|..|                       ||       :|.:||:||                 |:
Mosquito   293 YPYHH-----------------------QQ-------QQQQQQQQSAITHNNHSNSSILTSIEPI 327

  Fly   326 SEDACVDQTDA--GSSLNGST--TVLDNQPVAVENEPE-VKVAPPAATNGASTP-TPSHATPTVT 384
            |..:..|..:.  ||.||||:  .:||.   .:..|.| ::::....:||.:.| ...:|..|:|
Mosquito   328 STLSATDGANGTDGSPLNGSSCYAMLDE---FLSKEAESLRLSASNGSNGTTLPNADGNANSTLT 389

  Fly   385 ATATSSPSPT---------PTPVVAPVVTATPPPAAPAK---KEKLGGFLPNGCIFPRFKNNKHK 437
            :::::|.:||         ||...|...:|||.| .|||   |...|     ...||.|:::|..
Mosquito   390 SSSSASSTPTVPQTSPTNPPTSAAAAAASATPAP-VPAKEATKSSSG-----HTFFPMFRSSKSS 448

  Fly   438 DKD--------NSHKEGKSKEKTL----LNALKKSKEKKV-------------APS--------E 469
            ...        ||:....:...|.    |||..::.||..             ||:        |
Mosquito   449 SSSSSSSSTTTNSNSSSGANNNTANNAQLNAGSQAGEKPTVNGGSEPAAPVSSAPTTDSAQGAPE 513

  Fly   470 QPTEKAAASDNGTTQYEKNCINNLECEVQKLDLNSGTNGDNSMFIKLKVSPANATAAAAAAK 531
            .||.|||.:.:                     ..||.|    .|.:.|.|.|.|.:..|::|
Mosquito   514 PPTPKAAKTSS---------------------KKSGLN----FFRRNKSSTAAAASDTASSK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4022	NP_648307.1	alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	106..>196	CDD:469641	58/92 (63%)
LOC5667296	XP_061497138.1	None