Protein Alignment CG4022 and Nop17l

DIOPT Version :10

• Sequence 1: NP_648307.1
• Gene: CG4022 / 39082
• FlyBaseID: FBgn0035986
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_610324.2
• Gene: Nop17l / 35730
• FlyBaseID: FBgn0033224
• Length: 834
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 91/522 - (17%)
• Similarity: 163/522 - (31%)
• Gaps: 170/522 - (32%)

  Fly   106 PQPHMCIRTTTEAGEELFINVLSWTRIVIPQE--PSDPIPLYGGMRVPPGSPRSPPI-------- 160
            |:|...|:|..:...:.|||:.|...|..|:.  .:||   ..|.|   |...|.|:
  Fly    78 PKPGFVIKTALDGELKCFINIASCEEIQRPKNEVATDP---SSGSR---GLSWSIPMAQTTSRDD 136

  Fly   161 ---------VFAVMANPEVLKDSGRHSKDPEERRAMVELMCDFVEAMNPGVKLVRNAVILKDRDI 216
                     ||.|:.:|:.|..:.|:.   :.|:.:::...|.:|         |...:..||
  Fly   137 FDAKNNHCKVFDVVFHPDALHLAMRNK---QFRQCLIDTALDAIE---------REYKVSLDR-- 187

  Fly   217 SGELK----DVWNAVQAQRDREREEQMMQQRQQQHYQNITTQQMFPKSPDASRAASAGAAVNEAS 277
             ..||    |.....:....|:..:....:.|:.|    ....|||..|.|  .......|....
  Fly   188 -ANLKFPKLDYKGIPRPTVIRKMADNPTAEEQEPH----PLAHMFPTKPPA--PGKQEPRVLPMK 245

  Fly   278 SPPAHLSEPLLVEQGNGNGNGITLAVFAQQLDNKV------------------------------ 312
            :.|:.:.|..:......:.:.:.|:.:..:||.|:
  Fly   246 TKPSPVPEFTVPRYTIKHSHDVDLSEYTDELDAKLHVTVPRSLVVEIELPLLRSTAECQLDVTSK 310

  Fly   313 -----ASEQGEQQE--------------------------------QSPVSEDACVDQT------ 334
                 :..||.:..                                :..:.|.|.:.:|
  Fly   311 SIYLFSERQGAKYRLKLDLPFIVDDKAGRARFDTDMRRLSITLPVVRKSIQEQAQMHETLRHFSR 375

  Fly   335 -DAGSSLNGSTTVLDNQPVAVENEPEVKVAPPAATNGASTPTPSHATPTVTATATSSPSPTPTPV 398
             |:|..|:      .|....||.:|:.:::...|                ..:.|||||..|..
  Fly   376 EDSGVELH------SNSESPVEEDPDGELSDSKA----------------DISETSSPSVAPAN- 417

  Fly   399 VAPVVTATPPPAAPAKKEKLGGFLPNGCIFPRFKNNKHKDKDNSHKEGKSKEKTLLNALKKSKEK 463
             :|.:.::.....|:|.:  ...|.|...|.....|...|.....:|.:|..         .|..
  Fly   418 -SPFLKSSVHYQLPSKFD--CNVLDNVMAFVLHVPNVQPDSIEQLREQRSLH---------LKFA 470

  Fly   464 KVAPSEQPTEKAAASDNGTTQYEKNCINNLECEVQKLDLNSGTNGDNSMFIKLKVSPANATAAAA 528
            .:.....||..|...:. :.::|.:.|.:.|.|.          .||::.:||.::..:.|.|:.
  Fly   471 TIGSGYYPTHYAFYVEL-SAEHEDSSIESAEAEA----------WDNNVVLKLCLNSQSETPASY 524

  Fly   529 AA 530
            .|
  Fly   525 LA 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4022	NP_648307.1	alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	106..>196	CDD:469641	25/108 (23%)
Nop17l	NP_610324.2	PIH1	49..208	CDD:369738	32/150 (21%)
		PIH1_CS	254..356	CDD:408028	6/101 (6%)