Protein Alignment CG4022 and PIH1D2

DIOPT Version :9

• Sequence 1: NP_001246696.1
• Gene: CG4022 / 39082
• FlyBaseID: FBgn0035986
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_016872690.1
• Gene: PIH1D2 / 120379
• HGNCID: 25210
• Length: 316
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 78/363 - (21%)
• Similarity: 126/363 - (34%)
• Gaps: 98/363 - (26%)

  Fly    41 TTTNSYNNNLDTETQLQMHQDPQ------QQQELEGNSNNGITGLGLSLMNSSPPPHSYRHSRAY 99
            |....:.|.||...|    .||:      |||..||
Human    10 TQVTQFWNLLDDLAQ----SDPEGYEKFIQQQLKEG----------------------------- 41

  Fly   100 RHFKNPPQPHMCIRTTTEAGEE--LFINVLSWTRIVIPQEPSDPIPLYGGMRVPPGSPRSPPIVF 162
            :.....|:|.:|::|.....:|  ||||:..||||..||..:.|:||..|.............|.
Human    42 KQLCAAPEPQLCLQTRILKPKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVI 106

  Fly   163 AVMANPEVLKDSGRHSKDPEERRAMVELMCDFVEAMNPGVKLVRNAVILKDRDISGELKDVWNAV 227
            .|..||:||..:   .||..::..::::....:|.... ..|..:..|.|.| |.|.:
Human   107 DVAYNPDVLHAA---EKDQVKKNQLIQMAMKCIEEKFQ-FTLSHSYHITKFR-IKGSI------- 159

  Fly   228 QAQRDREREEQMMQQRQQQHYQNITTQQMFPKSPDASRAASAGAAVNEASSPPAHLSEPLLVEQG 292
                          ||.:|:...|.|..:..:. ...|..:.|...:...|.|.|..: ||:.:.
Human   160 --------------QRMKQNLMGIQTDSIDLRE-KMRRELTLGQIRSSTMSNPDHFPQ-LLLPKD 208

  Fly   293 NGNGNGITLAVFAQQLDNKVASEQGEQQEQSPVSEDACV-DQTDAGSSLNGSTTVLDNQPVAVEN 356
            ..:|..:.|.       .:::|.:.:.:.:.|..|...| |.::              :|:.:
Human   209 QVSGKAVCLI-------EEISSTEIQVEMKMPAYELKIVHDHSE--------------KPLKI-- 250

  Fly   357 EPEVKVAPPAATNGAS--TPTPSHATPTVTATATSSPS 392
              |:||..| ..|..|  ..:.|...|..|.|:.|..|
Human   251 --ELKVELP-GINSVSLCDLSVSETMPWDTLTSQSQAS 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4022	NP_001246696.1	alpha-crystallin-Hsps_p23-like	106..>196	CDD:294116	27/91 (30%)
PIH1D2	XP_016872690.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22997
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9704
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	4.020