Protein Alignment LAMA2 and mcp3

DIOPT Version :9

• Sequence 1: XP_016866340.1
• Gene: LAMA2 / 3908
• HGNCID: 6482
• Length: 3212
• Species: Homo sapiens
• Sequence 2: NP_594851.1
• Gene: mcp3 / 2543146
• PomBaseID: SPAC1006.04c
• Length: 952
• Species: Schizosaccharomyces pombe
• Alignment Length: 603
• Identity: 122/603 - (20%)
• Similarity: 244/603 - (40%)
• Gaps: 108/603 - (17%)

Human  1697 KMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMN-----ELLTRATKVTADGEQTGQ 1756
            |.:..|.::.:|||  |......::.:.|...:.|.|..:.|     :||.::..:.|...:..:
pombe   238 KRIAYLCSLVEELK--LHSSIMNDKYVCLVSKHNNALEDKFNSEAARQLLQKSLSIVASNLKQAE 300

Human  1757 D-----AERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIK 1816
            :     .|:.:....|:.| |:...||.:...||.....:.|..|:::.:..||.::.: ::.::
pombe   301 NKTISYEEKLSIAQNSINE-IQTQNRDLKLETEKLQDQIKALLERNQSLQEALETVKND-EKNLR 363

Human  1817 ELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREK--LADYKNKVDDAWDL 1879
            |: ..|.||:.:.|..:|...|||:......|.....:...:.:.||||  |.::::.|.:..||
pombe   364 EM-NANYETEMKEARQKLNNKEALISHYDDDFRAKELKISRLSESLREKAGLLEFQSSVSEQRDL 427

Human  1880 L--REATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSI 1942
            |  .:....|::...:|..|:..|..|.:.|..:|....::....:|...:.||.....|.:.|:
pombe   428 LYQEQIQSSIKDMENVFRKNEYLMEELNELKNNLEVESSKVLRLDEEMKCLKDEQLSQFDTVFSL 492

Human  1943 IDYVEDIQTKLPPMSEELNDKIDD---LSQEIKDRKLA-EKVSQAESHAAQLNDSSAVLDGILDE 2003
            .|..:.:|..|......|:|:|..   |..:|:|::|. ||:..:....:|.|:|   |...:.|
pombe   493 TDERDGLQKDLKNTKGNLDDEIGRSAFLKSQIRDQELTIEKLHDSLETLSQTNNS---LQCEISE 554

Human  2004 AKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL 2068
             ||...|:..                  :|.::..||..|  |.....:||:..:....|...:|
pombe   555 -KNAELNSVN------------------SKLSEGRAHLET--ANKENEILKQQLELSESKLASLL 598

Human  2069 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRT---LNDTLGKLSAIPN------------ 2118
            |..:...|    .::||......:|.:.|::.....|   :::::.|..:|.|
pombe   599 NSYQSFIN----KKEHLYSFLQLVEPSFAKSDSSNATESQISESVRKGISIFNLLFIVYKNVCSQ 659

Human  2119 ---DTAAKLQAVKDKARQANDTAKDVLAQIT-------ELHQNLDGLKKNY-----NKLADSVAK 2168
               :.:.||:.:.:      .|..|.|..||       :.:|..:...:||     :.|.|.:..
pombe   660 AGINPSTKLEDLDE------HTLSDELTYITKKFVQKDQEYQTKEIELRNYKITLQSLLEDKLIG 718

Human  2169 TNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANS 2233
            .|...:.||.:..        :.|.||:           |...::...:|::.:..|.:...:|:
pombe   719 VNTDCRSPSCSDF--------EQLGQES-----------ENNTSISGRVSKLVKSFNDSSSISNN 764

Human  2234 IKVSV--SSGGDCIRTYK 2249
            .|:|:  |..|:.:..:|
pombe   765 TKISITKSPSGEKVSVFK 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LAMA2	XP_016866340.1	None
mcp3	NP_594851.1	Lebercilin	314..504	CDD:292252	44/192 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030