DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4080 and Marchf1

DIOPT Version :9

Sequence 1:	NP_001246695.1	Gene:	CG4080 / 39079	FlyBaseID:	FBgn0035983	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	XP_017455664.2	Gene:	Marchf1 / 361135	RGDID:	1305148	Length:	542	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	95/190 - (50%)
Similarity:	134/190 - (70%)	Gaps:	16/190 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GSG-----SSQASQNSGD-------ICRICHCESDPQNPLLTPCYCSGSLKYVHQACLQQWLTAS 81
            |||     |:|.|..:.|       :|||||||.|.::||:|||.|:|:|::|||:||.||:.:|
  Rat   307 GSGLQLNTSTQKSPGADDDGSENFEVCRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSS 371

  Fly    82 ETNSCELCKFPFIMHTKIKPFNEWRSLDISGIERRRLCYSVLFHCAAALCVIWSLCVLIERAADD 146
            :|..|||||:.|||.||:||..:|..|.::..|||::..||.||..|..||:|||.|||:|.|::
  Rat   372 DTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAVTCVVWSLYVLIDRTAEE 436

  Fly   147 VQR----GLIDWPFWTKLAVVTVGLTGGIVFMYIQCKAYLHLCHRWKARNRILLIQNAPE 202
            :::    |:::|||||||.||.:|.|||:||||:|||.|:.|..|.||.||::.:||.|:
  Rat   437 IKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPD 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4080	NP_001246695.1	RINGv	42..90	CDD:128983	28/47 (60%)
Marchf1	XP_017455664.2	RING_CH-C4HC3_MARCH1_like	332..383	CDD:319612	30/50 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I7830
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001979
OrthoInspector	1	1.000	-	-		otm45080
orthoMCL	1	0.900	-	-		OOG6_106356
Panther	1	1.100	-	-	LDO	PTHR45981
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X270
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.770