DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4080 and marc-5

DIOPT Version :9

Sequence 1:	NP_001246695.1	Gene:	CG4080 / 39079	FlyBaseID:	FBgn0035983	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_496624.3	Gene:	marc-5 / 174876	WormBaseID:	WBGene00013273	Length:	601	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	65/235 - (27%)
Similarity:	95/235 - (40%)	Gaps:	58/235 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SQASQNSGDICRICHC--ESDPQNPLLTPCYCSGSLKYVHQACLQQWLTASETN-----SCELCK 90
            :::..::..:||||||  ..|..:||::||.|||||:|||.:||..||..|...     .||||.
Worm   315 ARSDMSNEPLCRICHCCWPPDSNDPLISPCRCSGSLQYVHVSCLMHWLDISSRKLHRPAICELCL 379

  Fly    91 FPFIMHTKIKPFNEWRSLDISGIERRRLCYSVLFHCAAALCVIWSLCVLIERAADDVQRGLIDWP 155
            :.: ...::..:.|.:                |..||.|                       |..
Worm   380 YKY-RRRRVLKYREMK----------------LPQCAQA-----------------------DIR 404

  Fly   156 FWTKLAVVTVGLTGGIVFMYIQC----KAYLHLCHRWKARNRI--LLIQNAPEKIHPVAPPS--P 212
            |:| |.||.:.|.....|..:.|    |:|.....:.:.|||.  |.::.....:.|.||||  .
Worm   405 FYT-LFVVAIVLMILSAFSTVVCFQLEKSYGLSSSQGELRNRTQPLNVEGVVSDVPPAAPPSLTA 468

  Fly   213 VAAHHQHFSEPLAHAGSTS--GAVEINASGAAGGYCAHEA 250
            ||...:..|.|....|:..  |.:.:|||.....|...||
Worm   469 VATASEESSVPTVVLGARKRIGDITVNASTKDESYRREEA 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4080	NP_001246695.1	RINGv	42..90	CDD:128983	27/54 (50%)
marc-5	NP_496624.3	RING_CH-C4HC3_MARCH	325..378	CDD:319409	26/52 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I6931
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001979
OrthoInspector	1	1.000	-	-		mtm4782
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R328
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840