DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4080 and march4l

DIOPT Version :9

Sequence 1:	NP_001246695.1	Gene:	CG4080 / 39079	FlyBaseID:	FBgn0035983	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_001038876.1	Gene:	march4l / 100000640	ZFINID:	ZDB-GENE-060825-323	Length:	421	Species:	Danio rerio

Alignment Length:	235	Identity:	60/235 - (25%)
Similarity:	101/235 - (42%)	Gaps:	59/235 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ICRICHCESDPQNPLLTPCYCSGSLKYVHQACLQQWLTASETNSCELC--KFPFIMHTKIKPFNE 104
            :||||. :...|..||:||.||||::..|:.||.:|::...:.|||||  |:..|..:...|. :
Zfish   142 LCRICF-QGPEQGELLSPCRCSGSVRCTHEPCLIKWISERGSWSCELCYYKYQVIAISTKNPL-Q 204

  Fly   105 WRSLDISGIERRRLCYSVLFHCAAALCVIWSLCVLIERAADDVQRGLIDWPFWTKLA-------- 161
            |:::.::.||:.::..:||    .:|.:|.|                |.|..|:.|:
Zfish   205 WQAISLTVIEKVQIAAAVL----GSLFLIAS----------------ISWLVWSSLSPSAKWQRQ 249

  Fly   162 ----VVTVGLTGGIVFMYIQCKAYL--------HLCHRWKARNRILLIQNAPEKIHPVAPPSPVA 214
                .:...:.|   ||.:.|.|.:        .:.:||:|.|:...:.|. :|:..........
Zfish   250 DLLFQICYAMYG---FMDLVCIALIVHEGPSVFRIFNRWQAVNQQWKVLNY-DKVKDNEDHQKTG 310

  Fly   215 AHHQHFSEPLAH-----------AGSTSGAVEINASGAAG 243
            |..:..|.||.|           :.|||..:...|:.|||
Zfish   311 ATFRTLSLPLTHRMGQSGPEGEPSTSTSSLMAAAAAAAAG 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4080	NP_001246695.1	RINGv	42..90	CDD:128983	22/49 (45%)
march4l	NP_001038876.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	60..79
		RINGv	143..188	CDD:128983	20/45 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..385		10/32 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..421
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810