DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp27 and HSPB9

DIOPT Version :9

Sequence 1:	NP_001287001.1	Gene:	Hsp27 / 39078	FlyBaseID:	FBgn0001226	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_149971.1	Gene:	HSPB9 / 94086	HGNCID:	30589	Length:	159	Species:	Homo sapiens

Alignment Length:	171	Identity:	41/171 - (23%)
Similarity:	62/171 - (36%)	Gaps:	55/171 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PRRLLLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPAVGKDGFQVCMDVSQFKPNELT 105
            |.|||          |.||..:....|                  .:||||:.:|...|.|.||.
Human    33 PVRLL----------RDSPAAQEDNDH------------------ARDGFQMKLDAHGFAPEELV 69

  Fly   106 VKVVDNTVVVEGKHE------EREDGHGMIQRHFVRKYTLPKGFDPNEVVSTVSSDGVLTLKAPP 164
            |:|....::|.|:.:      ||. .:.|.|:  |.:..||....|..:...::..|.|.::.
Human    70 VQVDGQWLMVTGQQQLDVRDPERV-SYRMSQK--VHRKMLPSNLSPTAMTCCLTPSGQLWVRG-- 129

  Fly   165 PPSKEQAKSERIVQIQQTGPAHLSVKAPAPEAGD--GKAEN 203
                 |..:..:.: .|||        |:|..|.  .||.|
Human   130 -----QCVALALPE-AQTG--------PSPRLGSLGSKASN 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	23/82 (28%)
HSPB9	NP_149971.1	ACD_HspB9_like	45..131	CDD:107236	24/113 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810