DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp27 and hspb8

DIOPT Version :9

Sequence 1:	NP_001287001.1	Gene:	Hsp27 / 39078	FlyBaseID:	FBgn0001226	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001005658.1	Gene:	hspb8 / 448147	XenbaseID:	XB-GENE-945643	Length:	202	Species:	Xenopus tropicalis

Alignment Length:	161	Identity:	52/161 - (32%)
Similarity:	78/161 - (48%)	Gaps:	24/161 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLEDDFGFGVHAHDL-------FHPRRLLL---PNTLGLGRRRYSP--YERSHGHHNQMSRRASG 76
            ||::|||....:.||       ..||....   |...||.|....|  |          :.|.:|
Frog    33 LLDEDFGIPPFSDDLTMDWPDWARPRLTSAWSGPLRSGLVRSGMPPPVY----------NSRYTG 87

  Fly    77 GPNALLPAVG-KDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLP 140
            .|:|...... ...::||::|..|||.|||||..|..|.|.|.|||::...|::.::|.:|:.||
Frog    88 YPDARNTVANISQPWKVCVNVQTFKPEELTVKTKDGFVEVSGNHEEQQKEGGIVSKNFTKKFQLP 152

  Fly   141 KGFDPNEVVSTVSSDGVLTLKAP-PPPSKEQ 170
            ...|...|.:::|.:|:|.::|| .||..:|
Frog   153 PEVDAQTVFASLSPEGLLIIEAPVVPPYNQQ 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	28/77 (36%)
hspb8	NP_001005658.1	alpha-crystallin-Hsps_p23-like	86..175	CDD:381838	31/88 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920