Protein Alignment Hsp27 and HSPB1

DIOPT Version :9

• Sequence 1: NP_001287001.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001531.1
• Gene: HSPB1 / 3315
• HGNCID: 5246
• Length: 205
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 56/139 - (40%)
• Similarity: 79/139 - (56%)
• Gaps: 7/139 - (5%)

  Fly    58 SPYERSHGHHNQMSRRASGGPNALLPAVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEER 122
            ||...:..:...:||:.|.|.:.:....  |.::|.:||:.|.|:|||||..|..|.:.||||||
Human    65 SPAVAAPAYSRALSRQLSSGVSEIRHTA--DRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEER 127

  Fly   123 EDGHGMIQRHFVRKYTLPKGFDPNEVVSTVSSDGVLTLKAPPPPSKEQAKSERIVQIQQTGPAHL 187
            :|.||.|.|.|.||||||.|.||.:|.|::|.:|.||::||.|....|: :|..:.:.....|.|
Human   128 QDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQS-NEITIPVTFESRAQL 191

  Fly   188 SVKAPAPEA 196
            .    .|||
Human   192 G----GPEA 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	40/76 (53%)
HSPB1	NP_001531.1	Interaction with TGFB1I1. /evidence=ECO:0000250	70..205		54/134 (40%)
		ACD_HspB1_like	84..169	CDD:107230	42/86 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820