Protein Alignment Hsp27 and Hspb6

DIOPT Version :10

• Sequence 1: NP_524000.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001012401.1
• Gene: Hspb6 / 243912
• MGIID: 2685325
• Length: 162
• Species: Mus musculus
• Alignment Length: 156
• Identity: 58/156 - (37%)
• Similarity: 77/156 - (49%)
• Gaps: 28/156 - (17%)

  Fly    22 GHLLEDDFGFGVHAHDLFHPRRLLLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPA-- 84
            |.|.:..||.|:...:|    ..|.|..:       :||          ..||   |:..||.
Mouse    26 GRLFDQRFGEGLLEAEL----ASLCPAAI-------APY----------YLRA---PSVALPTAQ 66

  Fly    85 VGKDG--FQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNE 147
            |..|.  |.|.:||..|.|.|::|||||:.|.|..:||||.|.||.|.|.|.|:|.||.|.||..
Mouse    67 VSTDSGYFSVLLDVKHFLPEEISVKVVDDHVEVHARHEERPDEHGFIAREFHRRYRLPPGVDPAA 131

  Fly   148 VVSTVSSDGVLTLKAPPPPSKEQAKS 173
            |.|.:|.:|||:::|.|..::.|..|
Mouse   132 VTSALSPEGVLSIQATPASAQAQLPS 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_524000.1	metazoan_ACD	86..163	CDD:107247	38/78 (49%)
Hspb6	NP_001012401.1	Involved in stabilization of the HSPB1:HSBP6 heterodimer. /evidence=ECO:0000250|UniProtKB:O14558	1..72		17/69 (25%)
		Crystallin	3..62	CDD:425732	13/59 (22%)
		ACD_HspB4-5-6	66..148	CDD:107233	40/81 (49%)