DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsp27 and hsp-25

DIOPT Version :9

Sequence 1:	NP_001287001.1	Gene:	Hsp27 / 39078	FlyBaseID:	FBgn0001226	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001024374.1	Gene:	hsp-25 / 180872	WormBaseID:	WBGene00002023	Length:	219	Species:	Caenorhabditis elegans

Alignment Length:	144	Identity:	44/144 - (30%)
Similarity:	74/144 - (51%)	Gaps:	32/144 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LGRRRYSPYERSHGHHNQMSRRASG-----------GPNALL---------------PAV--GKD 88
            :..:.|:.|..:..|| :.|.|..|           ||:.|:               |.:  ..|
Worm    72 ISNQPYNAYSNTSSHH-ETSNRTGGFGSPLPPPSFHGPSDLMAHRPTYDPYLDNLKSPLIKDESD 135

  Fly    89 G--FQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEVVST 151
            |  .::..||:.:||.|:|||.:||.::|..||||:.. ...:.|.:.:::.||:|.:|.::.||
Worm   136 GKTLRLRFDVANYKPEEVTVKTIDNRLLVHAKHEEKTP-QRTVFREYNQEFLLPRGTNPEQISST 199

  Fly   152 VSSDGVLTLKAPPP 165
            :|:|||||::||.|
Worm   200 LSTDGVLTVEAPLP 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	30/78 (38%)
hsp-25	NP_001024374.1	metazoan_ACD	131..212	CDD:107247	31/81 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920