Protein Alignment Hsp27 and CRYAA

DIOPT Version :9

• Sequence 1: NP_001287001.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_000385.1
• Gene: CRYAA / 1409
• HGNCID: 2388
• Length: 173
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 50/159 - (31%)
• Similarity: 76/159 - (47%)
• Gaps: 18/159 - (11%)

  Fly    24 LLEDDFGFGVHAHDLFHPRRLLLPNTLGLGRRRYSPYERSHGHHNQMSRRASGGPNALLPAVGKD 88
            |.:..||.|:..:||..    .|.:|:       |||.|.......:....|...:      .:|
Human    22 LFDQFFGEGLFEYDLLP----FLSSTI-------SPYYRQSLFRTVLDSGISEVRS------DRD 69

  Fly    89 GFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEVVSTVS 153
            .|.:.:||..|.|.:|||||.|:.|.:.|||.||:|.||.|.|.|.|:|.||...|.:.:..::|
Human    70 KFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLS 134

  Fly   154 SDGVLTLKAPP-PPSKEQAKSERIVQIQQ 181
            :||:||...|. ....:...:||.:.:.:
Human   135 ADGMLTFCGPKIQTGLDATHAERAIPVSR 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	34/76 (45%)
CRYAA	NP_000385.1	Crystallin	1..51	CDD:395419	12/39 (31%)
		ACD_alphaA-crystallin_HspB4	60..145	CDD:107245	35/90 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X393
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.920