Protein Alignment Hsp27 and Cryab

DIOPT Version :10

• Sequence 1: NP_524000.1
• Gene: Hsp27 / 39078
• FlyBaseID: FBgn0001226
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_034094.1
• Gene: Cryab / 12955
• MGIID: 88516
• Length: 175
• Species: Mus musculus
• Alignment Length: 185
• Identity: 64/185 - (34%)
• Similarity: 87/185 - (47%)
• Gaps: 42/185 - (22%)

  Fly    38 LFHP--RRLLLPNTLGLGRRRYSP---YERSHGHH----NQMSRRASGGPNALLP---------- 83
            :.||  ||...|        .:||   :::..|.|    :..|...|..|..|.|
Mouse     5 IHHPWIRRPFFP--------FHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWI 61

  Fly    84 -------AVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPK 141
                   .:.||.|.|.:||..|.|.||.|||:.:.:.|.||||||:|.||.|.|.|.|||.:|.
Mouse    62 DTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPA 126

  Fly   142 GFDPNEVVSTVSSDGVLTLKAPPPPSKEQAKSERIVQI-QQTGPAHLSVKAPAPE 195
            ..||..:.|::|||||||:..   |.|:.:..||.:.| ::..||    .|.||:
Mouse   127 DVDPLTITSSLSSDGVLTVNG---PRKQVSGPERTIPITREEKPA----VAAAPK 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_524000.1	metazoan_ACD	86..163	CDD:107247	40/76 (53%)
Cryab	NP_034094.1	Crystallin	1..55	CDD:425732	14/57 (25%)
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	41/85 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..175		10/37 (27%)