DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp27 and hspb2

DIOPT Version :9

Sequence 1:	NP_001287001.1	Gene:	Hsp27 / 39078	FlyBaseID:	FBgn0001226	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	XP_002932983.1	Gene:	hspb2 / 100497635	XenbaseID:	XB-GENE-940436	Length:	179	Species:	Xenopus tropicalis

Alignment Length:	180	Identity:	55/180 - (30%)
Similarity:	84/180 - (46%)	Gaps:	41/180 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLEDDFGFGVHAHDLFHPRRLLLPNTLGLGRRRYSPYERSHGHH-----NQMSRRASGGPNALLP 83
            :.:.:||.|:...||..|       ||            .||::     |:.:.|.....|.
Frog    24 IFDQNFGEGISPEDLLCP-------TL------------YHGYYIRPRINKQTDRGFSEINR--- 66

  Fly    84 AVGKDGFQVCMDVSQFKPNELTVKVVDNTVVVEGKHEEREDGHGMIQRHFVRKYTLPKGFDPNEV 148
              .:..|||.:||..|.|:|::|..:||.:.|..||.::.|.||.:.|.|.|||.||...||..|
Frog    67 --NEHKFQVFLDVCHFLPDEISVHTMDNLLEVSAKHPQKIDSHGFVSRSFNRKYILPLDVDPLLV 129

  Fly   149 VSTVSSDGVLTLKAPPPPSKE-QAKSE-RIVQIQQTGPAHLSVKAPAPEA 196
            .:.:|.||:|:::|   |.|| ..|.| .:|:|:..       ::|..||
Frog   130 KAKLSHDGILSIEA---PRKEVDLKGENNVVKIKVQ-------RSPVAEA 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp27	NP_001287001.1	metazoan_ACD	86..163	CDD:107247	31/76 (41%)
hspb2	XP_002932983.1	Crystallin	<21..51	CDD:278926	10/45 (22%)
		IbpA	<63..149	CDD:223149	36/93 (39%)
		alpha-crystallin-Hsps_p23-like	69..145	CDD:294116	32/78 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920