DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hsp23 and HSPB2

DIOPT Version :9

Sequence 1:NP_001246694.1 Gene:Hsp23 / 39077 FlyBaseID:FBgn0001224 Length:186 Species:Drosophila melanogaster
Sequence 2:NP_001532.1 Gene:HSPB2 / 3316 HGNCID:5247 Length:182 Species:Homo sapiens


Alignment Length:161 Identity:48/161 - (29%)
Similarity:72/161 - (44%) Gaps:32/161 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 YEPYYCQRQRNPYLALVGPMEQQLRQLEKQVGASSGSSGAVSKI----GKDGFQVCMDVSHFKPS 83
            |..||.:.:..|                    |..||....|::    ||  ||..:|||||.|.
Human    44 YHGYYVRPRAAP--------------------AGEGSRAGASELRLSEGK--FQAFLDVSHFTPD 86

  Fly    84 ELVVKVQDNSVLVEGNHEEREDDHGFITRHFVRRYALPPGYEADKVASTLSSDGVLTIKVPKPPA 148
            |:.|:..||.:.|...|.:|.|.|||::|.|.|.|.||...:..:|.:.||.||:|.::.|:   
Human    87 EVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPR--- 148

  Fly   149 IEDKGNERIVQIQQVGPAHLNVKENPKEAVE 179
               .|.....::.:|..:.|....:|:|..|
Human   149 ---GGRHLDTEVNEVYISLLPAPPDPEEEEE 176

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hsp23NP_001246694.1 metazoan_ACD 67..145 CDD:107247 33/77 (43%)
IbpA <69..161 CDD:223149 33/91 (36%)
HSPB2NP_001532.1 alpha-crystallin-Hsps_p23-like 67..148 CDD:412199 33/82 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148883
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1187096at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
54.710

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