DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp67Ba and Hspb7

DIOPT Version :9

Sequence 1:	NP_523998.1	Gene:	Hsp67Ba / 39076	FlyBaseID:	FBgn0001227	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_038896.2	Gene:	Hspb7 / 29818	MGIID:	1352494	Length:	169	Species:	Mus musculus

Alignment Length:	181	Identity:	39/181 - (21%)
Similarity:	61/181 - (33%)	Gaps:	72/181 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RSLAMDIDDSAGFGLYPLEATSQLPQLSRGLGRGNAMMWVPIKGQSAASQHRHHPYNRVAGAKTA 83
            ::|:|..||   ||.:.|..:..|...:|..|:||.
Mouse    42 KALSMFSDD---FGSFMLPHSEPLAFPARPGGQGNI----------------------------- 74

  Fly    84 CCNKSLVELEKELGDKGTSGASGSTSGQPAASKSAYSVVNRNGFQVSMNVKQFAANELTVKTIDN 148
                      |.|||                           .::.:::::.|:..::.|.|.:|
Mouse    75 ----------KTLGD---------------------------AYEFTVDMRDFSPEDIIVTTFNN 102

  Fly   149 CIVVEGQHDEKEDGHGVISRHFIRKYILPKGYDPNEVHSTLSSDGILTVKA 199
            .|.|..   ||....|.:...|..|..||:..||..|.|.|..||.||::|
Mouse   103 HIEVRA---EKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRA 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp67Ba	NP_523998.1	metazoan_ACD	124..200	CDD:107247	23/76 (30%)
Hsp67Ba	NP_523998.1	DNA_pol3_delta2	<218..>381	CDD:331068
Hspb7	NP_038896.2	Required for localization to SC35 splicing speckles. /evidence=ECO:0000250	1..70		9/30 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		ACD_HspB7_like	72..152	CDD:107234	29/148 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740