DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsp67Ba and hsp-25

DIOPT Version :9

Sequence 1:	NP_523998.1	Gene:	Hsp67Ba / 39076	FlyBaseID:	FBgn0001227	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001024374.1	Gene:	hsp-25 / 180872	WormBaseID:	WBGene00002023	Length:	219	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	58/220 - (26%)
Similarity:	97/220 - (44%)	Gaps:	46/220 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLAEELHDFNRSLAMDIDDSAG-----FGLYPLEATSQLPQLSRGLGRGNAMMWVPIKGQSAASQ 68
            :::|...|.|||....||:..|     |.........::.:|     |.....:.|..|..||..
Worm    14 EMSERRIDVNRSNYSVIDNEFGNMRDRFEQEMRRVEEEMKRL-----RSEFEGYRPNGGPPAAIS 73

  Fly    69 HRHHPYNRVAGAKTACCNKSLVELEKELGDKGTSGASGSTSGQPA--------ASKSAYSVVNRN 125
            ::  |||  |.:.|:..:::          ...:|..||....|:        |.:..|.....|
Worm    74 NQ--PYN--AYSNTSSHHET----------SNRTGGFGSPLPPPSFHGPSDLMAHRPTYDPYLDN 124

  Fly   126 -------------GFQVSMNVKQFAANELTVKTIDNCIVVEGQHDEKEDGHGVISRHFIRKYILP 177
                         ..::..:|..:...|:|||||||.::|..:|:||.....|. |.:.::::||
Worm   125 LKSPLIKDESDGKTLRLRFDVANYKPEEVTVKTIDNRLLVHAKHEEKTPQRTVF-REYNQEFLLP 188

  Fly   178 KGYDPNEVHSTLSSDGILTVKAPPP 202
            :|.:|.::.||||:||:|||:||.|
Worm   189 RGTNPEQISSTLSTDGVLTVEAPLP 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp67Ba	NP_523998.1	metazoan_ACD	124..200	CDD:107247	29/88 (33%)
Hsp67Ba	NP_523998.1	DNA_pol3_delta2	<218..>381	CDD:331068
hsp-25	NP_001024374.1	metazoan_ACD	131..212	CDD:107247	29/81 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6558
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.950