DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp67Ba and Hspb8

DIOPT Version :9

Sequence 1:	NP_523998.1	Gene:	Hsp67Ba / 39076	FlyBaseID:	FBgn0001227	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_446064.1	Gene:	Hspb8 / 113906	RGDID:	71003	Length:	196	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	54/218 - (24%)
Similarity:	86/218 - (39%)	Gaps:	73/218 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IDDSAGFGLYPLEATS-----QLPQLSRG---------LGRG---NAMMWVPIKGQSAASQHRHH 72
            :||..|...:|.:.|:     .||:||..         :.||   .|...||.:|::..
  Rat    31 LDDGFGMDPFPDDLTAPWPEWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRNPP------ 89

  Fly    73 PYNRVAGAKTACCNKSLVELEKELGDKGTSGASGSTSGQPAASKSAYSVVNRNGFQVSMNVKQFA 137
            |:                                  .|:|              ::|.:||..|.
  Rat    90 PF----------------------------------PGEP--------------WKVCVNVHSFK 106

  Fly   138 ANELTVKTIDNCIVVEGQHDEKEDGHGVISRHFIRKYILPKGYDPNEVHSTLSSDGILTVKAP-- 200
            ..||.|||.|..:.|.|:|:||:...|::|::|.:|..||...||..|.::||.:|:|.::||
  Rat   107 PEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQV 171

  Fly   201 PPLPVVKGSLERQERIVDIQQIS 223
            ||......|....|...|.|:::
  Rat   172 PPYSPFGESSFNNELPQDNQEVT 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp67Ba	NP_523998.1	metazoan_ACD	124..200	CDD:107247	28/75 (37%)
Hsp67Ba	NP_523998.1	DNA_pol3_delta2	<218..>381	CDD:331068	2/6 (33%)
Hspb8	NP_446064.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		ACD_HspB8_like	80..170	CDD:107235	35/143 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..196		4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342805
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750