DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp26 and Hspb8

DIOPT Version :9

Sequence 1:	NP_001287000.1	Gene:	Hsp26 / 39075	FlyBaseID:	FBgn0001225	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_109629.1	Gene:	Hspb8 / 80888	MGIID:	2135756	Length:	196	Species:	Mus musculus

Alignment Length:	110	Identity:	36/110 - (32%)
Similarity:	56/110 - (50%)	Gaps:	15/110 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 LRREMANRNDIHWPATAHVG------------KDGFQVCMDVAQFKPSELNVKVVDDSILVEGKH 118
            ||..|..|..   ||||..|            .:.::||::|..|||.||.||..|..:.|.|||
Mouse    64 LRSGMVPRGP---PATARFGVPAEGRSPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKH 125

  Fly   119 EERQDDHGHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPK 163
            ||:|.:.|.:.::|.::.::|.......|.:.||.:|:|.:..|:
Mouse   126 EEKQQEGGIVSKNFTKKIQLPAEVDPATVFASLSPEGLLIIEAPQ 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp26	NP_001287000.1	metazoan_ACD	85..163	CDD:107247	27/89 (30%)
Hsp26	NP_001287000.1	IbpA	<87..179	CDD:223149	27/77 (35%)
Hspb8	NP_109629.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		ACD_HspB8_like	80..170	CDD:107235	27/89 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..196
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740