DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsp26 and hspb1

DIOPT Version :9

Sequence 1:	NP_001287000.1	Gene:	Hsp26 / 39075	FlyBaseID:	FBgn0001225	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_001072817.1	Gene:	hspb1 / 780278	XenbaseID:	XB-GENE-480320	Length:	211	Species:	Xenopus tropicalis

Alignment Length:	150	Identity:	50/150 - (33%)
Similarity:	80/150 - (53%)	Gaps:	16/150 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 PSSPAGQVL-----ALRREMANR-NDIHWPATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILV 114
            |::|||...     ||.|::::. ::|...:      |.:::.:||..|.|.||.:|..|..:.:
Frog    68 PTTPAGATAPDFNRALSRQLSSGISEIRQTS------DQWKISLDVNHFAPEELVIKTKDGIVEI 126

  Fly   115 EGKHEERQDDHGHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPKPQAVEDKSKERIIQIQ 179
            .|||||:||:||.|.|.|.|:|.:|.|....:|.|.||.||:|||..|.|:.....::   |.|.
Frog   127 TGKHEEKQDEHGFISRCFTRKYTLPPGVDINKVASSLSPDGILTVEAPLPKPAIQSAE---IAIP 188

  Fly   180 QVGPAHLNVKANESEVKGKE 199
            ....:...:...|:: ||:|
Frog   189 ITFQSRAEIGTTEAK-KGEE 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsp26	NP_001287000.1	metazoan_ACD	85..163	CDD:107247	34/77 (44%)
Hsp26	NP_001287000.1	IbpA	<87..179	CDD:223149	37/91 (41%)
hspb1	NP_001072817.1	ACD_HspB1_like	90..175	CDD:107230	35/90 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I6892
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010