DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hsp26 and HSPB2

DIOPT Version :9

Sequence 1:NP_001287000.1 Gene:Hsp26 / 39075 FlyBaseID:FBgn0001225 Length:208 Species:Drosophila melanogaster
Sequence 2:NP_001532.1 Gene:HSPB2 / 3316 HGNCID:5247 Length:182 Species:Homo sapiens


Alignment Length:178 Identity:46/178 - (25%)
Similarity:67/178 - (37%) Gaps:57/178 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 GLGLHP---------HSRYVLPLGTQQRRSINGCPCASPICPSSPAGQVLALRREMANRNDIHWP 79
            |.||.|         |..||.|.             |:|....|.||                 .
Human    30 GEGLLPEEILTPTLYHGYYVRPR-------------AAPAGEGSRAG-----------------A 64

  Fly    80 ATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILVEGKHEERQDDHGHIMRHFVRRYKVPDGYKA 144
            :...:.:..||..:||:.|.|.|:.|:.||:.:.|..:|.:|.|.||.:.|.|.|.|.:|.....
Human    65 SELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDP 129

  Fly   145 EQVVSQLSSDGVLTVSIPKPQAVEDKSKERIIQIQQVGPAHLNVKANE 192
            .:|.:.||.||:|.:..|:                  |..||:.:.||
Human   130 WRVRAALSHDGILNLEAPR------------------GGRHLDTEVNE 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hsp26NP_001287000.1 metazoan_ACD 85..163 CDD:107247 27/77 (35%)
IbpA <87..179 CDD:223149 28/91 (31%)
HSPB2NP_001532.1 alpha-crystallin-Hsps_p23-like 67..148 CDD:412199 27/80 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148885
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1187096at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
54.710

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