Protein Alignment Hsp26 and Hspb1

DIOPT Version :10

• Sequence 1: NP_523997.1
• Gene: Hsp26 / 39075
• FlyBaseID: FBgn0001225
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_038588.2
• Gene: Hspb1 / 15507
• MGIID: 96240
• Length: 209
• Species: Mus musculus
• Alignment Length: 207
• Identity: 70/207 - (33%)
• Similarity: 97/207 - (46%)
• Gaps: 37/207 - (17%)

  Fly    17 RSPIYELGLGLHP-HSRYV--------LPLGTQQRRSINGCPCASPICPSS----PAGQVL---- 64
            |||.:|.....:| |||..        ||....|..|..|.|......|::    ||...|
Mouse    12 RSPSWEPFRDWYPAHSRLFDQAFGVPRLPDEWSQWFSAAGWPGYVRPLPAATAEGPAAVTLAAPA 76

  Fly    65 ---ALRREMANR-NDIHWPATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILVEGKHEERQDDH 125
               ||.|::::. ::|...|      |.::|.:||..|.|.||.||..:..:.:.||||||||:|
Mouse    77 FSRALNRQLSSGVSEIRQTA------DRWRVSLDVNHFAPEELTVKTKEGVVEITGKHEERQDEH 135

  Fly   126 GHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPKPQAVEDKSKERI-----IQIQQVGPAH 185
            |:|.|.|.|:|.:|.|.....|.|.||.:|.|||..|.|:||...::..|     .:.|..||
Mouse   136 GYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQSAEITIPVTFEARAQIGGP-- 198

  Fly   186 LNVKANESEVKG 197
               :|.:||..|
Mouse   199 ---EAGKSEQSG 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp26	NP_523997.1	metazoan_ACD	85..163	CDD:107247	35/77 (45%)
Hspb1	NP_038588.2	Interaction with TGFB1I1. /evidence=ECO:0000250	74..209		52/145 (36%)
		ACD_HspB1_like	88..173	CDD:107230	37/90 (41%)