DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4461 and HSPB6

DIOPT Version :9

Sequence 1:NP_648304.1 Gene:CG4461 / 39074 FlyBaseID:FBgn0035982 Length:200 Species:Drosophila melanogaster
Sequence 2:NP_653218.1 Gene:HSPB6 / 126393 HGNCID:26511 Length:160 Species:Homo sapiens


Alignment Length:93 Identity:35/93 - (37%)
Similarity:51/93 - (54%) Gaps:6/93 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 RVHVDEKGFRIDIDVRQFHPHDIVVKTNDDYVIVQGNHNRRDEGSNGLVERHFVRKYLLPRGYNA 154
            :|..|...|.:.:||:.|.|.:|.||...::|.|...|..|.: .:|.|.|.|.|:|.||.|.:.
Human    66 QVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPD-EHGFVAREFHRRYRLPPGVDP 129

  Fly   155 NEVISDISSDGILTIKAPP-----PPPA 177
            ..|.|.:|.:|:|:|:|.|     ||||
Human   130 AAVTSALSPEGVLSIQAAPASAQAPPPA 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4461NP_648304.1 metazoan_ACD 94..169 CDD:107247 27/74 (36%)
HSPB6NP_653218.1 Involved in stabilization of the HSPB1:HSBP6 heterodimer. /evidence=ECO:0000269|PubMed:27717639 1..72 2/5 (40%)
Crystallin 3..58 CDD:395419
ACD_HspB4-5-6 66..144 CDD:107233 28/78 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1187096at2759
OrthoFinder 1 1.000 - - FOG0000383
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45640
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X393
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
55.020

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