DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4461 and Hspb8

DIOPT Version :9

Sequence 1:	NP_648304.1	Gene:	CG4461 / 39074	FlyBaseID:	FBgn0035982	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_446064.1	Gene:	Hspb8 / 113906	RGDID:	71003	Length:	196	Species:	Rattus norvegicus

Alignment Length:	184	Identity:	51/184 - (27%)
Similarity:	82/184 - (44%)	Gaps:	43/184 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DSRLWWPSPHTS--RSDLLRPLDELVSRRVRNQLIQSTPY---------EWAHPMRWDNYYSG-- 88
            |.:|.:|..:.|  |.|..|  |..:|.|:.:......|:         |||.| |..:.:.|
  Rat     3 DGQLPFPCSYPSRLRRDPFR--DSPLSSRLLDDGFGMDPFPDDLTAPWPEWALP-RLSSAWPGTL 64

  Fly    89 ------------ERVHVDEKG----------FRIDIDVRQFHPHDIVVKTNDDYVIVQGNHNRRD 131
                        .|..|..:|          :::.::|..|.|.:::|||.|.||.|.|.|..:.
  Rat    65 RSGMVPRGPTATARFGVPAEGRNPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQ 129

  Fly   132 EGSNGLVERHFVRKYLLPRGYNANEVISDISSDGILTIKAPPPPPAKYYTP-GE 184
            : ..|:|.::|.:|..||...:...|.:.:|.:|:|.|:||..||   |:| ||
  Rat   130 Q-EGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPP---YSPFGE 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4461	NP_648304.1	metazoan_ACD	94..169	CDD:107247	23/84 (27%)
Hspb8	NP_446064.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		8/26 (31%)
		ACD_HspB8_like	80..170	CDD:107235	26/90 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..196		3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820